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Hallucinogens are drugs that cause hallucinations or distortions in a person's perception of reality. Hallucinations are described as seeing images or hearing sounds that are not actually present and can result from medications, disease, mental illness, and even insomnia. This entry is concerned with the history, effects, and classification of hallucinogens that are discussed and/or used most frequently: lysergic acid diethylamide (LSD), phencyclidine (PCP), ketamine (known on the street as Special K), psilocybin (street name, magic mushrooms), mescaline (peyote), meth-ylenedioxymethamphetamine (MDMA or ecstasy) and dimethyltryptamine (DMT). However, drugs that are not labeled hallucinogens, such as marijuana and cocaine, may cause hallucinations when taken in high doses or combined with other drugs.

Hallucinogens challenge what one knows and believes about human behavior and how the brain works. They have raised an abundant amount of controversy, and there are many different opinions regarding whether the effects of hallucinogens are positive or negative. Several researchers have labeled hallucinogens among the safest illicit drugs since they are not physically addictive. However, the heavy use of hallucinogens can result in a psychological dependence, and hallucinogen use disorders are included as diagnostic categories in the Diagnostic and Statistical Manual of Mental Disorders. There are no known physical withdrawal symptoms associated with hallucinogens, and overdosing is rare.

The federal government categorizes most hallucinogens as Schedule I drugs, the classification used for the most dangerous drugs in the United States. Schedule I drugs have high potential for abuse and have no known recognized medical use. With the exception of ketamine (used as an animal tranquil-izer), hallucinogens have no recognized medical use in the United States and are illegal to possess.

History

Several different cultures have utilized hallucinogens for centuries. Hallucinogens have been used for social purposes, rituals, and ceremonies. Indigenous peoples discovered hallucinogens in plant form and integrated them into their religious belief patterns. Traditionally, it was believed that hallucinogens created an enlightened sense of spirituality, opened users to the gods, and provided them with greater spiritual insight. These beliefs still hold true in some North and South American countries, as well as some Asian countries such as Malaysia and Borneo.

Hallucinogens have been used in medicine and research. In the 1950s, PCP was developed for use as an anesthetic in medical procedures. The use of PCP was short-lived because the effects were extreme and dangerous. Instead, ketamine was designed as a safer replacement. Additionally, researchers wanted to identify how hallucinogens work in the brain, and this desire led to the widespread use of LSD and ecstasy by psychiatrists and researchers in the 1950s. LSD specifically was used for therapy in an attempt to aid individuals in exploring thoughts and in expressing feelings.

Hallucinogens are notorious for their seemingly mind-expanding effects. As a result, there have been documented increases in the use of hallucinogens for recreational purposes during certain periods of time. For example, LSD was discovered in 1938 by Dr. Albert Hofmann, but it was not until the 1960s' freedom movement that hallucinogens became popular for recreational use. During this time, hallucinogens were considered mind-enhancing psychedelics, and LSD became a widespread drug of choice for many people.

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