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Drug Use, History of
Certainly one, among many things, at which humans consistently excel is the willingness and desire to alter our consciousness and augment our sensory experiences. The vehicle for humans from prehistoric time to current day is the use of drugs to quickly accomplish this goal (although there are a host of nondrug practices to equally alter consciousness, such as meditation). The large majority of humanity does not suffer from drug addiction; yet, members of every human culture (from Aboriginal to Indian, Chinese, Egyptian, South American, Aleuts, Chukchi, and Eskimo) use psychoactive drugs on a daily basis for a variety of reasons (i.e., pain relief, religious, vision seeking, consciousness expansion, entertainment, as a food source, healing disease, and even seeking immortality).
Historically, the vast majority of drugs used by humans were hallucinogens, and few were central nervous system stimulants or depressants. A mere 300 years ago, plants and fungi were the major sources of psychoactive chemicals, as humans had not yet become clever enough to reproduce complex synthesis routes that plants accomplish with only water, earth, and sunlight. There are over 800,000 species of plants living today; a small fraction of these species (about 4,000) are the best producers of psychoactive substances on the planet, and they were most convenient for human discovery and use.
Why Plants and Fungi Produce Psychoactive Substances
One theory about the purpose underlying the variety of psychoactive chemicals synthesized by plants is believed to be as a chemical defense against organisms that would consume them. Eating a plant or fungus containing psychoactives would disrupt the central nervous system of the animal via stimulant (organism becomes hyperactive, or anorectic and ceases eating the plant) or depressant (organism becomes sleepy and eating ceases). If additional plant substance continued to be consumed, the dose could rise to lethal levels in the case of stimulant and depressant plant substances. Plants and fungi producing hallucinogens (the main effect is to disrupt sensory systems) and eaten by mammals would most likely result in an aver si ve event for the mammal. Again, the organism would discontinue eating.
According to Ronald K. Siegal, practically all animals consume plants and fungi that contain psychoactive substances. Humans could have watched animals eat plants with psychoactive properties and imitated them to develop drug use patterns in neolithic ages. Elephants, koalas, goats, cows, cats, reindeer, rabbits, mice, and birds, respectively, eat fermented fruit (alcohol), eucalyptus leaves, caffeine, locoweed, catnip, mushrooms, belladonna in wild lettuce, and hempseed. An interesting observation is that animals do not seem to prefer the effects of hallucinogens (as demonstrated by drug self-administration research studies). Only humans are known to regularly consume hallucinogens voluntarily and for entertainment purposes.
Drugs of Abuse: Ancient Use History
The study of drug use in humans before the common era (bc) overlaps several areas of study and can include ethnobotony, archeopharmacology, ethno-pharmacology, and the history of drug use with regard to tracing prehistoric, neolithic medicinal and religious plant use in humans. Note that the "factual" dating of evidence in excess of 300 years prior to the common era is considered imprecise and, in many instances, are simply good guesses based on some empirical evidence (i.e., radiocarbon dating, uncovering burial remains, chemical analyses of residue for pottery). For instance, among the oldest reports of evidence in the family Hominidae is archeological evidence of H. neanderthalensis burial sites in Iraq from 50,000 years ago. Examination of plant remains reveals the presence of the natural stimulant herbal ephedra. This evidence seems to support the conclusion that Neanderthals used psychoactive drugs. However, the oldest drugs used by humans, that today are considered drugs of abuse, include depressants, stimulants, and hallucinogens.
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- Behavioral Addictions
- Classifications of Drugs of Abuse
- Alcohol
- Amphetamines
- Amyl Nitrite
- Anabolic Steroids
- Anxiolytic Drugs
- Barbiturates
- Benzodiazepines
- Buprenorphine
- Caffeine
- Central Nervous System Depressants
- Central Nervous System Stimulants
- Club Drugs
- Cocaine and Crack
- Drugs, Classification of
- Ecstasy
- Fentanyl
- Hallucinogens
- Heroin
- Illicit and Illegal Drugs
- Inhalants
- Levo-Alpha Acetyl Methadol
- Marijuana
- Methadone
- Methamphetamine
- Methods of Drug Administration
- Morphine
- Naltrexone
- Opioids
- Over-the-Counter Drugs
- OxyContin
- Prescription Drugs
- Tobacco
- Criminal Justice System and Substance Abuse
- Engagement and Intervention
- Family and Community Issues
- Adult Children of Alcoholics
- Al-Anon
- Alateen
- Behavioral Couples Therapy
- Binge Drinking
- Brief Strategic Family Therapy
- Children of Alcoholics
- Codependency
- Community Reinforcement and Family Training
- Community Reinforcement Approach
- Enabling
- Experimental Substance Use
- Family Behavior Therapy
- Family Therapy
- Fetal Alcohol Syndrome
- Fetal Effects of Alcohol and Other Drugs
- Multidimensional Family Therapy
- Violence, Intimate Partner and Substance Abuse Treatment
- Models of Addiction
- Neurobiology of Addiction
- Prevention Theories, Research, Techniques, Strategies, and Effectiveness
- Alcohol Marketing
- Alternative Activities
- Behavioral Risk Factor Surveillance System
- Community-Based Processes
- Drug Abuse Resistance Education
- Environmental Approaches
- Evidence-Based Prevention
- Evidence-Based Prevention and Treatment, Dissemination and Adoption of
- Expectancies
- Fidelity of Prevention Programs
- Gateway Drugs Theory
- High-Risk Behaviors
- Information Dissemination
- Institute of Medicine Classification System
- Mentoring
- Monitoring the Future
- National Clearinghouse for Alcohol and Drug Information
- National Media Campaign
- National Outcome Measures
- National Registry of Evidence-based Programs and Practices
- National Survey on Drug Use and Health
- Prevention Education
- Prevention Evaluation
- Prevention Populations
- Prevention Resources
- Prevention Strategies
- Problem Identification and Referral
- Public Policy, Prevention
- Racial and Ethnic Minorities, Issues in Prevention
- Refusal Skills
- Risk and Protective Factor Theory
- Risk Factors for Addiction
- School-Based Prevention Programs
- Social Norms Marketing
- Social Skills Training
- Tobacco Marketing and Countermarketing
- Tobacco Master Settlement Agreement
- Underage Drinking
- Violence Prevention
- Professional Issues in Addictions
- Addiction Technology Transfer Centers
- American Society of Addiction Medicine
- Business Improvement Practices
- Centers for the Application of Prevention Technologies
- Certification and Licensing
- Clinical Supervision of Addiction Counselors
- College on Problems of Drug Dependence
- Confidentiality
- Dual Relationships
- Electronic Health Records
- Ethical Standards for Addiction Professionals
- Ethics
- Health Insurance Portability and Accountability Act
- Impaired Professionals
- Informed Consent
- International Coalition for Addiction Studies Education
- NAADAC, the Association for Addiction Professionals
- Network for the Improvement of Addiction Treatment
- Qualified Services Organization Agreements
- Single State Authorities
- State Provider Associations
- Public Policy Development
- Access to Recovery
- Center for Substance Abuse Prevention
- Center for Substance Abuse Treatment
- Comprehensive Drug Abuse Prevention and Control Act
- Decriminalization
- Demand Reduction
- Discrimination, Addicted and Recovering Individuals
- Drug Testing
- Drug-Free Schools and Communities Act
- Economic Costs of Alcohol and Drug Abuse
- Harm Reduction, Public Health
- Indian Health Services
- Insurance Parity
- Join Together
- Legal Action Center
- Legalization of Drugs
- Medical Use of Marijuana
- Moderation Approaches to Alcohol Problems
- National Council on Alcoholism and Drug Dependence
- National Drug Control Strategy
- National Epidemiologie Survey on Alcohol and Related Conditions
- National Institute of Mental Health
- National Registry of Evidence-based Programs and Practices
- Needle Exchange Programs
- Office of National Drug Control Policy
- Public Policy, Alcohol
- Public Policy, Drugs
- Public Policy, Prevention
- Public Policy, Treatment
- pulse Check
- Single State Authorities
- State Provider Associations
- Substance Abuse and Mental Health Services Administration
- Supply Reduction
- Synar Amendment
- Tobacco Master Settlement Agreement
- War on Drugs
- Recovery
- Al-Anon
- Alateen
- Alcoholics Anonymous
- Big Book, The
- Bill W.
- Cocaine Anonymous
- Double Trouble
- Dry Drunk Syndrome
- Gamblers Anonymous
- Moderation in Use
- Moderation Management
- Narcotics Anonymous
- Natural Recovery
- Peer Recovery Support Services
- Rational Recovery
- Recovery
- Recovery Community Organizations
- Recovery Community Services Program
- Recovery Schools
- Recovery Support Services
- Secular Organizations for Sobriety/Save Our Selves
- Sobriety
- Social Drinking
- Spiritual Issues
- Stigma
- Support Groups
- Twelve Steps
- Twelve-Step Recovery Programs
- Women for Sobriety
- Relapse Prevention
- Research and Evaluation Issues in Substance Abuse Prevention and Treatment
- Cannabis Youth Treatment Study
- College on Problems of Drug Dependence
- COMBINE Study
- Drug Abuse Treatment Outcome Studies
- Evidence-Based Prevention
- Evidence-Based Prevention and Treatment, Dissemination and Adoption of
- Evidence-Based Treatment
- Fidelity of Prevention Programs
- National Institute on Alcohol Abuse and Alcoholism
- National Institute on Drug Abuse
- National Institute on Drug Abuse Clinical Trials Network
- National Treatment Improvement Evaluation Study
- Prevention Evaluation
- Project MATCH
- Research Issues in Prevention
- Research Issues in Treatment
- Screening, Assessment, and Diagnosis
- Addiction Severity Index
- Alcohol Testing
- Alcohol Use Disorders Identification Test
- Alcohol-Induced Disorders
- Alcoholism
- Antisocial Personality Disorder
- Anxiety Disorders
- Assessment
- Assessment Instruments
- Borderline Personality Disorder
- CAGE Screening Instrument
- Co-Occurring Disorders
- Denial
- Depression
- Diagnosis
- Diagnostic and Statistical Manual of Mental Disorders
- Drug Abuse Screening Test
- Drug Testing
- Experimental Substance Use
- Inventory of Drinking Situations
- Michigan Alcohol Screening Test
- Post-Traumatic Stress Disorder
- Problem Oriented Screening Instrument for Teenagers
- Psychosocial History
- Screening
- Screening Instruments
- Self-Report Inventories
- Substance Abuse
- Substance Abuse Subtle Screening Inventory-3
- Substance Dependence
- Substance Use Disorders
- Substance-Induced Disorders
- Substance-Induced Withdrawal Delirium
- Timeline Followback
- Tolerance
- Urine Toxicology Testing
- Withdrawal
- Sociocultural and Historical Perspectives on Drug use
- Special Populations: Etiology, Prevention, and Treatment
- Adolescents, Substance Abuse and Treatment
- Antisocial Personality Disorder
- Anxiety Disorders
- Athletes and Drug Use
- Borderline Personality Disorder
- Children of Alcoholics
- Co-Occurring Disorders
- College Students, Alcohol Use and Abuse
- College Students, Drug Use and Abuse
- Criminal Justice Populations
- Depression
- Disabilities, Issues in Prevention and Treatment
- Elderly Populations, Treatment Issues
- Fetal Alcohol Syndrome
- Fetal Effects of Alcohol and Other Drugs
- Gay, Lesbian, Bisexual, and Transgender Issues
- Gender Issues
- Homeless, Substance Abuse and Treatment
- Maternal Drug Use
- Multiculturalism
- Post-Traumatic Stress Disorder
- Racial and Ethnic Minorities, Issues in Alcohol and Other Drug Use
- Racial and Ethnic Minorities, Issues in Prevention
- Racial and Ethnic Minorities, Issues in Treatment
- Special Populations
- Veterans, Substance Abuse and Treatment
- Welfare Reform and Substance Abuse
- Substance Abuse Health-Related Issues
- Alcohol-Related Birth Defects
- Amotivational Syndrome
- Antidepressant Drugs
- Antipsychotic Drugs
- Antiseizure Drugs
- Anxiolytic Drugs
- Attention Deficit Hyperactivity Disorder
- Blood Alcohol Concentration
- Drug Abuse Warning Network
- Fetal Alcohol Syndrome
- Fetal Effects of Alcohol and Other Drugs
- Grief, Loss, and Substance Abuse
- Health Care System and Substance Abuse
- Hepatitis C
- HIV/AIDS
- Injection Drug Use
- Insurance Parity
- Maternal Drug Use
- Medical Consequences
- Medical Use of Marijuana
- Methods of Drug Administration
- Pain Management
- Sexually Transmitted Diseases
- Suicide
- Tuberculosis
- Substance Abuse in the Workplace and School
- Treatment Theories, Research, Techniques, Strategies, and Effectiveness
- Abstinence Violation Effect
- Acamprosate
- Acceptance and Commitment Therapy
- Antabuse (Disulfiram)
- Antisocial Personality Disorder
- Anxiety Disorders
- Aversive Therapy
- Behavioral Couples Therapy
- Borderline Personality Disorder
- Brief Interventions
- Brief Strategic Family Therapy
- Buprenorphine
- Cannabis Youth Treatment Study
- CENAPS Model
- Client Engagement
- Client/Treatment Matching
- Co-Occurring Disorders
- Cognitive Behavioral Therapy
- Cognitive-Social Learning Model
- COMBINE Study
- Community Reinforcement and Family Training
- Community Reinforcement Approach
- Contingency Management
- Continuum of Care
- Counseling Approaches
- Court-Mandated Treatment
- Covert Sensitization
- Craving
- Depression
- Detoxification
- Drug Abuse Treatment Outcome Studies
- Evidence-Based Prevention and Treatment, Dissemination and Adoption of
- Evidence-Based Treatment
- Family Behavior Therapy
- Family Therapy
- Gender Issues
- Grief, Loss, and Substance Abuse
- Group Therapy and Counseling
- Harm Reduction Psychotherapy
- Inventory of Drinking Situations
- Levo-Alpha Acetyl Methadol
- Matrix Model
- Methadone Maintenance Treatment
- Minnesota Model
- Moderation Approaches to Alcohol Problems
- Moderation in Use
- Motivational Enhancement Therapy
- Motivational Interviewing
- Multidimensional Family Therapy
- Naloxone
- Naltrexone
- National Outcome Measures
- National Treatment Improvement Evaluation Study
- Nicotine Replacement Therapy
- Outpatient Treatment
- Patient Placement Criteria
- Pharmacological Approaches to Treatment
- Post-Traumatic Stress Disorder
- Project MATCH
- Public Policy, Treatment
- Qualified Services Organization Agreements
- Racial and Ethnic Minorities, Issues in Treatment
- Rapid Opioid Detoxification
- Relapse
- Relapse Prevention
- Residential Treatment
- Resistance in Treatment
- Solution-Focused Therapy
- Stages of Change Model
- Substitute Addictions
- Support Groups
- Synanon
- Therapeutic Communities
- Tobacco Cessation Programs and Treatments
- Treatment Access and Retention
- Treatment Approaches and Strategies
- Treatment Effectiveness
- Treatment Facilities
- Treatment in Jails and Prisons
- Treatment of Alcohol and Drug Use Disorders
- Treatment Plans and Treatment Planning
- Treatment Programs for Alcohol or Drug Abuse
- Treatment Settings
- Treatment, Nontraditional Approaches
- Twelve-Step Facilitation
- Veterans, Substance Abuse and Treatment
- Violence, Intimate Partner and Substance Abuse Treatment
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