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Co-occurring disorders are a combination of a substance use disorder (abuse or dependence) and another mental disorder, as established in the fourth text revision edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) of the American Psychological Association. It is estimated that 50% to 70% of people diagnosed with either a mental disorder or a substance use disorder will have a co-occurring disorder of the other type; therefore, it is crucial to address the topic of co-occurring disorders. This entry discusses a brief history of co-occurring disorders, incidence and prevalence, screening, assessment, treatment planning, treatment interventions and programs, and evidence-based practices. A list of resources for further information is also included.

Definitions of Terms

A vast number of combinations of disorders have been labeled co-occurring disorders. These include co-occurring substance use disorders in combination with mental disorders, serious mental illnesses, developmental disabilities, health or physical diagnoses, or personality disorders. The term also refers to a combination of substance use disorders (e.g., cocaine dependence and alcohol dependence) or a combination of mental disorders (e.g., depression and schizophrenia or an anxiety disorder co-occurring with a personality disorder). For the purposes of this entry, co-occurring disorders is defined as co-occurring substance use disorders (abuse or dependence) and mental disorders, as established in the DSM-IV-TR. A diagnosis of co-occurring disorders can be made when at least one disorder of each type can be established independently of the other, when neither can be documented as a cluster of symptoms resulting from the other.

Substance Use Disorders

Substance abuse, as defined by the DSM-IV-TR, is a maladaptive pattern of substance use leading to clinically significant impairment or distress. Substance abuse is manifested by recurrent and significant negative or adverse consequences related to the recurrent use of substances. These negative consequences include repeated failure to fulfill major responsibilities at work, school, or home; repeated use in situations that are physically hazardous; and recurrent legal, social, or interpersonal problems related to the use of the substance.

According to the DSM-IV-TR, substance dependence is a maladaptive pattern of substance use, leading to clinically significant impairment or distress. It can be manifested by increased tolerance, a withdrawal syndrome, and/or a number of behavioral symptoms. These symptoms include having a desire to cut down or control the use of the substance; using the substance more than was intended; giving up important social, occupational, or recreational activities; or continuing to use despite knowledge that use affects a recurrent physical or mental health problem. The essential feature of substance dependence is impaired control over the use of the substance.

Mental Disorders

The DSM-IV-TR also provides the standard diagnostic criteria for mental disorders that comprise co-occurring disorders. Co-occurring mental disorders fall under a number of different categories. These include affective disorders, anxiety disorders, psychotic disorders, and personality disorders.

Affective disorders (also referred to as mood disorders) are characterized by persistent or episodic exaggerations of emotional states. Some examples of the emotional states include depression, mania, euphoria, dysphoria, anger, and irritability.

Anxiety disorders are characterized by felt anxiety at a frequency or intensity that causes impairment in functioning. Other symptoms may include affective flattening, alogia, apathy, avolition, and social withdrawal. Anxiety disorders include social phobia, panic disorder, and post-traumatic stress disorders.

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