Entry
Reader's guide
Entries A-Z
Subject index
Wisconsin
SITUATED IN THE northern portion of the Midwestern United States, Wisconsin is widely known as the Dairy State in recognition of its prodigious production of cheese and other dairy products. It is also the site of numerous important scientific, industrial, and cultural contributions throughout its development into a modern and multi—faceted state. Wisconsin is also renowned within the stem cell field as a hub for new research and innovation, centered primarily at the University of Wisconsin, Madison.
Wisconsin was incorporated as the 30th state of the United States of America on May 29, 1848. Wisconsin's capital was eventually established in Madison, although its largest city is Milwaukee. In its early history, Wisconsin was populated primarily by immigrants from New York State, who brought the large—scale dairy farming methods that helped shape the agriculture of Wisconsin. Throughout the second half of the nineteenth century, Wisconsin became an increasingly diverse state, incorporating successive waves of immigrants from Europe, particularly from Germany and the Scandinavian nations. Because of the heavy influence of German culture and heritage in Wisconsin, the state is sometimes dubbed the most German—American state in the Union. This is reflected in many of the cultural traditions of the state, such as Oktoberfest. Wisconsin also contains large populations of people descended from Norwegian and Scandinavian roots, as well as many Asian ethnic groups, including the Hmong. Following the Vietnam War, several cities in Wisconsin were selected as resettlement sites for Hmong refugees displaced by the conflict.
The state of Wisconsin is recognized for its high—quality cheeses and dairy production. The state is also proud of its National Football League championship team, the Green Bay Packers; the Milwaukee Brewers, a Major League Baseball team; and the Milwaukee Bucks of the National Basketball Association.
Involvement in Stem Cell Research
Researchers based in Wisconsin conducted much of the pioneering research in the stem cell field. Dr. James Thomson at the University of Wisconsin, Madison was the first to isolate and culture primate embryonic stem cells in 1995, following this discovery with the successful isolation and culture of human embryonic stem cells in 1998. University of Wisconsin researchers also announced in 2001 that they had successfully induced embryonic stem cells to differentiate into primitive blood cells, and eventually other hema—topoietic cells. Many other research milestones in the stem cell field have also been achieved by scientists based in Wisconsin.
Stem cell research continues to expand and flourish in Wisconsin, and researchers are increasingly focusing on new applications for stem cells. Ongoing research efforts focus on regenerative medicine and on application to specific conditions such as cardiovascular disease, cancer, and neurodegenerative diseases.
Research Infrastructure
A number of important Wisconsin institutions have developed into a supporting infrastructure for advancing stem cell research efforts. One of the chief components of this infrastructure is the state—funded and state—supported University of Wisconsin system, which has been instrumental in many of the key discoveries and advances in stem cell biology. Another key component of Wisconsin's stem cell infrastructure is WiCell, a supporting agency of the University of Wisconsin. WiCell is a provider and distributor of the five unique human embryonic stem cell lines developed at the University of Wisconsin, Madison, providing cells to universities and accredited researchers across the country. WiCell also works to develop research protocols and training programs to advance stem cell research nationally and internationally. WiCell is also designated by the federal government as the site of the National Stem Cell Bank, which holds the 21 human embryonic stem cell lines available for use in federally funded research.
...
- Biology
- Biotechnology, History of
- Cell Sorting
- Cells, Adult
- Cells, Amniotic
- Cells, Developing
- Cells, Embryonic
- Cells, Fetal
- Cells, Human
- Cells, Monkey
- Cells, Mouse (Embryonic)
- Cells, Neural
- Cells, Sources of
- Cells, Umbilical
- Cytogenetic Instability of Stem Cells
- Developmental Biology
- Differentiation, In Vitro and In Vivo
- Division Types (Symmetrical and Asymmetrical)
- Experimental Models
- Feeder/Feeder—Free Culture
- Gut Stem Cells
- Induced Pluripotent Stem Cells
- Lineages
- Mammary Stem Cells
- Markers of Sternness
- Methods of Growing Cells
- Microenvironment and Immune Issues
- Neuralstem
- Neurosphere Cultures
- Niche Self—Renewal
- Nuclear Reprogramming
- Parthogenesis
- Plant Stem Cells
- Prostate Tissue Stem Cells
- Renal Stem Cells
- Self—Renewal, Stem Cell
- Stem Cell Applications, Articular Cartilage
- Stem Cell Applications, Tendon and Ligament
- Stem—Like Cells, Human Brain
- Tissue Culture
- Transdifferentiation
- Clinical Trials
- Clinical Trials Outside U.S.: Amyotrophic Lateral Sclerosis
- Clinical Trials Outside U.S.: Avascular Necrosis
- Clinical Trials Outside U.S.: Severe Coronary Artery Disease
- Clinical Trials Outside U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Batten Disease
- Clinical Trials Within U.S.: Blind Process
- Clinical Trials Within U.S.: Cancer
- Clinical Trials Within U.S.: Heart Disease
- Clinical Trials Within U.S.: Peripheral Vascular Disease
- Clinical Trials Within U.S.: Skin Transplants (Burns)
- Clinical Trials Within U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Traumatic Brain Injury
- Clinical Trials Worldwide
- Countries
- Diseases
- Ethics
- History and Technology
- Birth Dating of Cells by Retrovirus
- Bone Marrow Transplants
- BrdU/Thymidine
- Fluorescence—Activated Cell Sorting
- Human Embryonic Stem Cells
- In Vitro Fertilization
- Mouse ES Cell Isolation
- MRI Tracking
- Non—Human Primate Embryonic Stem Cells
- Nuclear Transfer, Altered
- Nuclear Transfer, Somatic
- Parthogenesis
- Preimplantation Genetic Diagnosis
- Viral Vectors: Adeno—Associated Virus
- Viral Vectors: Adenovirus
- Viral Vectors: Lentivirus
- Industry
- Institutions
- Albert Einstein College of Medicine
- Baylor College of Medicine
- Bonn University
- Burnham Institute
- Caltech
- Cambridge University
- Case Western Reserve University/Cleveland Clinic
- Children's Hospital, Boston
- Columbia University
- Coriell Institute
- Duke University
- Genetics Policy Institute
- Harvard University
- Indiana University
- Johns Hopkins University
- Kyoto University
- Massachusetts General Hospital
- Massachusetts Institute of Technology
- Mayo Clinic
- McMaster University
- Mount Sinai School of Medicine
- National Academy of Science
- Northwestern University
- Oregon Health & Science University
- Ottawa Health Research Institute
- Oxford University
- Princeton University
- Reeve—Irvine Research Center
- Robarts Research Institute
- Rockefeller University
- Rutgers University
- Salk Institute
- Scripps Research Institute
- Sloan—Kettering Institute
- Stanford University
- Stowers Institute
- University of California, Berkeley
- University of California, Davis
- University of California, Los Angeles
- University of California, San Diego
- University of California, San Francisco
- University of Connecticut
- University of Georgia
- University of Miami
- University of Michigan
- University of Minnesota
- University of North Carolina, Chapel Hill
- University of Pittsburgh
- University of Southern California
- University of Texas Health Science Center at Houston
- University of Toronto
- University of Washington/Hutchinson Cancer Center
- University of Wisconsin, Madison
- Vanderbilt of University
- Wake Forest University
- Weill—Cornell Medical College
- Whitehead Institute
- Yale University
- Legal Issues
- Organizations
- American Association for the Advancement of Science
- Australian Stem Cell Centre
- California Institute for Regenerative Medicine
- Canadian Stem Cell Network
- China Stem Cell News
- Christopher Reeve Foundation
- Community of Stem Cell Scientists
- Danish Stem Cell Research Center
- East of England Stem Cell Network
- European Consortium for Stem Cell Research—EuroStemCell
- International Society for Stem Cell Research
- International Stem Cell Forum
- Japan Human Cell Society
- Lasker Foundation
- Medical Research Council UK Stem Cell Initiative
- Michael J. Fox Foundation
- National Institutes of Health
- National Stem Cell Bank
- Parkinson's Disease Foundation
- Scottish Stem Cell Network
- Stem Cell Genome Anatomy Projects
- Swiss Stem Cell Network
- UK National Stem Cell Network
- Wisconsin Alumni Research Foundation
- People
- Alvarez—Buylla, Arturo
- Anversa, Piero
- Charo, Robin Alta
- Eaves, Connie
- Eggan, Kevin
- Fuchs, Elaine
- Gage, Fred
- Gearhart, John
- Goldman, Steven A.
- Jaenisch, Rudolf
- Keller, Gordon
- Kriegstein, Arnold
- Lanza, Robert
- Losordo, Douglas
- Macklis, Jeffrey
- McKay, Ronald D. G.
- Melton, Doug
- Morrison, Sean
- Mummery, Christine
- Nottebohm, Fernando
- Okano, Hideyuki
- Orkin, Stuart
- Rao, Mahendra
- Smith, Austin
- Snyder, Evan
- Steindler, Dennis A.
- Studer, Lorenz P.
- Thomson, James
- Van der Kooy, Derek
- Verfaillie, Catherine
- Vescovi, Angelo
- Weissman, Irving
- Wilmut, Ian
- Politics
- Advocacy
- Coalition for the Advancement of Medical Research
- Congress: Votes and Amendments (Cloning/Embryos)
- Dickey Amendment
- Do No Harm: The Coalition of Americans for Research Ethics
- National Right to Life Committee
- President's Council on Bioethics
- Presidential Campaigns
- Reagan, Nancy
- Special Interest/Lobby Groups
- Stem Cells, Bush Ruling
- Religion
- States
- Alabama
- Arizona
- Arkansas
- California
- Colorado
- Connecticut
- Delaware
- Florida
- Georgia
- Hawaii
- Idaho
- Illinois
- Indiana
- Iowa
- Kansas
- Kentucky
- Louisiana
- Maine
- Maryland
- Massachusetts
- Michigan
- Minnesota
- Mississippi
- Missouri
- Montana
- Nebraska
- Nevada
- New Hampshire
- New Jersey
- New Mexico
- New York
- North Carolina
- North Dakota
- Ohio
- Oklahoma
- Oregon
- Pennsylvania
- Rhode Island
- South Carolina
- South Dakota
- Tennessee
- Texas
- Utah
- Vermont
- Virginia
- Washington
- West Virginia
- Wisconsin
- Wyoming
- Loading...
Get a 30 day FREE TRIAL
-
Watch videos from a variety of sources bringing classroom topics to life
-
Read modern, diverse business cases
-
Explore hundreds of books and reference titles
Sage Recommends
We found other relevant content for you on other Sage platforms.
Have you created a personal profile? Login or create a profile so that you can save clips, playlists and searches