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Whitehead Institute
THE WHITEHEAD INSTITUTE for Biomédical Research is a unique and innovative research institution that stresses creativity and scientific innovation primarily focused in the biological and biomédical sciences. The Whitehead Institute is the product of a partnership between the Massachusetts Institute of Technology (MIT) and Edwin C. Whitehead, a philanthropist who donated substantial funding to establish the Whitehead Institute in 1982. Today, the Whitehead Institute is a vibrant research institution that continues to play an important and leading role in many areas of biological research, including the stem cell field.
Philosophy and History of the Whitehead Institute
Edwin C. Whitehead, a wealthy businessman and philanthropist, conceived the original vision of the Whitehead Institute. Whitehead recognized the value of direct research as a means to develop therapies to help cure some of the most intractable diseases. He searched for a major research institution with which he could partner to make this vision a reality. Finally, he contacted professor and well—known Nobel laureate David Baltimore of MIT. MIT is well recognized as an important research institution that has contributed widely throughout many scientific and engineering fields and is the birthplace of many advanced technologies.
The idea was to create a new kind of institution that allowed individual scientists the freedom to pursue their interests and specialties. At the same time, the goal of the Whitehead Institute is to provide the tools and infrastructure to allow scientists working in disparate fields to come together and collaborate, forming partnerships that normally would not be possible.
Another key component of the Whitehead Institute that would develop over the years is the institute's commitment to retaining highly engaged faculty. The institute also has sought to limit the number of faculty members and the size of the institution to facilitate increased cooperation and collaboration among the Whitehead community of scientists.
Biomedical Research Realized
The idea of the Whitehead Institute was fully realized in 1982, when an agreement was reached between Whitehead and MIT. MIT agreed to provide faculty for the institute, and Whitehead agreed to provide the largest individual gift to biomédical research at that time of $135 million. In 1984, the Whitehead Institute opened its doors in Cambridge, Massachusetts, in a $35 million state—of the—art facility.
The staff and faculty of the Whitehead Institute also study a wide range of disciplines. Staff and faculty members at the institute have included botanists, engineers, geneticists, molecular biologists, and many others from disparate fields. The goal of the institute in bringing all of these fields together is to create innovation and to foster cooperation that crosses academic lines in the interest of developing new techniques and partnerships to advance scientific research, and hopefully generate results that lead to more effective therapies.
Since its inception, the Whitehead Institute for Biomédical Research has been widely recognized as a pioneering and important institution. In 1990, after only 8 years in existence, the Institute for Scientific Information listed the Whitehead Institute as the top institution in the world in molecular biology and genetics. The research accomplishments of the Whitehead Institute are diverse and cover a broad range of specialties and fields within the biomédical arena. As the human genome project was conceived and accomplished, the Whitehead Institute was noted in particular for its prominent leadership role through Dr. Eric Lander and his research group, leading to the establishment of a new sister institution nearby, the Broad Institute, which focuses on genomic research.
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- Biology
- Biotechnology, History of
- Cell Sorting
- Cells, Adult
- Cells, Amniotic
- Cells, Developing
- Cells, Embryonic
- Cells, Fetal
- Cells, Human
- Cells, Monkey
- Cells, Mouse (Embryonic)
- Cells, Neural
- Cells, Sources of
- Cells, Umbilical
- Cytogenetic Instability of Stem Cells
- Developmental Biology
- Differentiation, In Vitro and In Vivo
- Division Types (Symmetrical and Asymmetrical)
- Experimental Models
- Feeder/Feeder—Free Culture
- Gut Stem Cells
- Induced Pluripotent Stem Cells
- Lineages
- Mammary Stem Cells
- Markers of Sternness
- Methods of Growing Cells
- Microenvironment and Immune Issues
- Neuralstem
- Neurosphere Cultures
- Niche Self—Renewal
- Nuclear Reprogramming
- Parthogenesis
- Plant Stem Cells
- Prostate Tissue Stem Cells
- Renal Stem Cells
- Self—Renewal, Stem Cell
- Stem Cell Applications, Articular Cartilage
- Stem Cell Applications, Tendon and Ligament
- Stem—Like Cells, Human Brain
- Tissue Culture
- Transdifferentiation
- Clinical Trials
- Clinical Trials Outside U.S.: Amyotrophic Lateral Sclerosis
- Clinical Trials Outside U.S.: Avascular Necrosis
- Clinical Trials Outside U.S.: Severe Coronary Artery Disease
- Clinical Trials Outside U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Batten Disease
- Clinical Trials Within U.S.: Blind Process
- Clinical Trials Within U.S.: Cancer
- Clinical Trials Within U.S.: Heart Disease
- Clinical Trials Within U.S.: Peripheral Vascular Disease
- Clinical Trials Within U.S.: Skin Transplants (Burns)
- Clinical Trials Within U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Traumatic Brain Injury
- Clinical Trials Worldwide
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- Ethics
- History and Technology
- Birth Dating of Cells by Retrovirus
- Bone Marrow Transplants
- BrdU/Thymidine
- Fluorescence—Activated Cell Sorting
- Human Embryonic Stem Cells
- In Vitro Fertilization
- Mouse ES Cell Isolation
- MRI Tracking
- Non—Human Primate Embryonic Stem Cells
- Nuclear Transfer, Altered
- Nuclear Transfer, Somatic
- Parthogenesis
- Preimplantation Genetic Diagnosis
- Viral Vectors: Adeno—Associated Virus
- Viral Vectors: Adenovirus
- Viral Vectors: Lentivirus
- Industry
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- Albert Einstein College of Medicine
- Baylor College of Medicine
- Bonn University
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- Genetics Policy Institute
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- University of Washington/Hutchinson Cancer Center
- University of Wisconsin, Madison
- Vanderbilt of University
- Wake Forest University
- Weill—Cornell Medical College
- Whitehead Institute
- Yale University
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- American Association for the Advancement of Science
- Australian Stem Cell Centre
- California Institute for Regenerative Medicine
- Canadian Stem Cell Network
- China Stem Cell News
- Christopher Reeve Foundation
- Community of Stem Cell Scientists
- Danish Stem Cell Research Center
- East of England Stem Cell Network
- European Consortium for Stem Cell Research—EuroStemCell
- International Society for Stem Cell Research
- International Stem Cell Forum
- Japan Human Cell Society
- Lasker Foundation
- Medical Research Council UK Stem Cell Initiative
- Michael J. Fox Foundation
- National Institutes of Health
- National Stem Cell Bank
- Parkinson's Disease Foundation
- Scottish Stem Cell Network
- Stem Cell Genome Anatomy Projects
- Swiss Stem Cell Network
- UK National Stem Cell Network
- Wisconsin Alumni Research Foundation
- People
- Alvarez—Buylla, Arturo
- Anversa, Piero
- Charo, Robin Alta
- Eaves, Connie
- Eggan, Kevin
- Fuchs, Elaine
- Gage, Fred
- Gearhart, John
- Goldman, Steven A.
- Jaenisch, Rudolf
- Keller, Gordon
- Kriegstein, Arnold
- Lanza, Robert
- Losordo, Douglas
- Macklis, Jeffrey
- McKay, Ronald D. G.
- Melton, Doug
- Morrison, Sean
- Mummery, Christine
- Nottebohm, Fernando
- Okano, Hideyuki
- Orkin, Stuart
- Rao, Mahendra
- Smith, Austin
- Snyder, Evan
- Steindler, Dennis A.
- Studer, Lorenz P.
- Thomson, James
- Van der Kooy, Derek
- Verfaillie, Catherine
- Vescovi, Angelo
- Weissman, Irving
- Wilmut, Ian
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- Dickey Amendment
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- Reagan, Nancy
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