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University of California, Los Angeles

THE UNIVERSITY OF California, Los Angeles (UCLA), is a state (public) research university located in Los Angeles, California. UCLA has the largest enrollment of any university in the state. In 2005, UCLA announced its plan to establish the Institute for Stem Cell Biology and Medicine (ISCBM). The state of California provides public funding of research with new embryonic stem cell lines, and in this regard it is unique. The Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA was initiated by Chancellor Albert Carnesale and the deans of the UCLA schools and college in March 2005. UCLA committed over $20 million over five years. UCLA and its sister University of California schools, Berkeley, Davis, San Diego, and San Francisco, have made great advances in stem cell research, largely because of California's avid state—support of stem cell research.

UCLA realizes the importance of the interdis—ciplinarity of its faculty members and institutions and emphasizes a close, ongoing collaboration of the university's scientific, medical, and academic disciplines. UCLA collaborators include the AIDS Institute, UCLA Center for Society and Genetics, Jonsson Comprehensive Cancer Center, Brain Research Institute, California NanoSys—tems Institute, College of Letters and Sciences, and schools of engineering, dentistry, medicine, law, nursing, and public affairs.

UCLA publications make this interdisciplinary and intercollegiate effort much easier; UCLA news, college reports, journals of clinical investigations, UCLA Magazine, UCLA Medicine, and the Associated Press have all reported on advancements in stem cell research at UCLA.

Eli and Edythe Broad Center

In September 2007, a formal ceremony and conference recognized the Eli and Edythe Broad Foundation, an organization that provided a gift of $20 million to the UCLA ISCBM, and the institute was renamed the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA. The center states that it is “committed to a multi—disciplinary, campus—wide, integrated, collaboration of scientific, academic, and medical disciplines for the purpose of understanding adult and human embryonic stem cells. The ISCBM supports innovation, excellence, and the highest ethical standards focused on stem cell research with the intent of facilitating basic scientific inquiry directed towards future clinical applications in the treatment of disease.”

UCLA also has a strong history of translational research—the branch of medical research that connects research in the laboratory (basic research) to patient care (bedside). The research focus at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA focuses on neural stem cells; HIV/AIDS; metabolic disorders; hematopoietic and immune systems; cancer stem cells; muscle, bone, and cartilage; human embryotic stem cell gene expression, genomic reprogramming, and human embryotic stem cell growth and differentiation.

A Unique Policy

In June 2007, President George W. Bush vetoed the Stem Cell Research Enhancement Act. Bush did, however, issue an executive order that encouraged alternative methods for the derivation of stem cells (other than purely embryonic methodology); these alternative methods of research would, in fact, be eligible for National Institutes of Health funding. A second veto was issued on the Stem Cell Research Enhancement Act by the president, however; this bill proposed to magnify the federal support of embryonic stem cell research that followed specific guidelines.

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