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University of California, Davis
THE UNIVERSITY OF California, Davis (UCD), is a public research university, the main campus of which is located in Davis, California, near Sacramento; the UCD Medical School is located in Sacramento. It is one of 10 universities within the University of California system and was the third branch of the University of California. It began in 1905 as an agricultural school known as the university farm. UCD became a general campus within the University of California system in 1959; this includes the UC Davis School of Medicine, which was founded in 1966. In 2006, UCD enrolled over 23,000 undergraduate and 4,000 graduate and 2,900 professional students and employed over 10,000 academic staff members including almost 2,500 faculty members and over 20,000 support staff members.
The Stem Cell Program at UCD is a multidis—ciplinary enterprise involving faculty members and researchers from the school of medicine and other parts of the university, including biological sciences, veterinary medicine, engineering, business, law, and bioethics. The program's overarching goal is to develop stem cell therapies to prevent, treat, or cure human diseases. This goal will be realized through three types of activities, as detailed on the program's Web page: performance of detailed comparisons of adult stem cells, and those from a variety of age groups, with human embryonic stem cells differentiated toward defined lineages using animal models of health and disease, including immunodeficient mice, small and large animal models, and nonhuman primate models; facilitation and enhancement of collaborations between basic, translation, and clinical faculty members in disease—specific focus groups; and the performance of high—quality, basic and translational research leading to clinical trials for stem and progenitor cell—mediated tissue repair and regeneration. Researchers in the program currently (in 2007) work with adult stem cells but may some day include embryonic stem cells as well, when questions of safety and efficacy are resolved.
Stem Cell Center
A new facility to house the UCD Stem Cell Center is expected to be completed in downtown Sacramento, near the UCD Medical Center, in September 2008. It will include laboratory and support space, a shared vector core, an immunodeficient mouse/toxicology vivarium and microscopy core, a cell sorter core, and space for offices, training, and conference rooms. The new facility will also house a Good Manufacturing Practice facility, which will play an important role in the center's goal of facilitating movement of the cellular therapies studied in animal models into human clinical trials.
UCD physicians and researchers have been in the forefront of stem cell research, a fact attested to by their success in attracted funding. In 2005, UCD was named by the National Institutes of Health as one of only two Centers of Excellence for translational human stem cell research in the United States; the new center created with this funding is called the Center for Pédiatrie Stem and Progenitor Cell Translational Research. In addition, UCD received one of the first grants bestowed by the California Institute for Regenerative Medicine (CIRM), a state agency that disburses funds for stem cell research, raised by a bond issue and private donations, to establish a research and training program for young scientists. UCD also received multiyear research grants totaling about $8 million from CIRM in 2007 and an additional $2.8 million in capital construction grants.
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- Biology
- Biotechnology, History of
- Cell Sorting
- Cells, Adult
- Cells, Amniotic
- Cells, Developing
- Cells, Embryonic
- Cells, Fetal
- Cells, Human
- Cells, Monkey
- Cells, Mouse (Embryonic)
- Cells, Neural
- Cells, Sources of
- Cells, Umbilical
- Cytogenetic Instability of Stem Cells
- Developmental Biology
- Differentiation, In Vitro and In Vivo
- Division Types (Symmetrical and Asymmetrical)
- Experimental Models
- Feeder/Feeder—Free Culture
- Gut Stem Cells
- Induced Pluripotent Stem Cells
- Lineages
- Mammary Stem Cells
- Markers of Sternness
- Methods of Growing Cells
- Microenvironment and Immune Issues
- Neuralstem
- Neurosphere Cultures
- Niche Self—Renewal
- Nuclear Reprogramming
- Parthogenesis
- Plant Stem Cells
- Prostate Tissue Stem Cells
- Renal Stem Cells
- Self—Renewal, Stem Cell
- Stem Cell Applications, Articular Cartilage
- Stem Cell Applications, Tendon and Ligament
- Stem—Like Cells, Human Brain
- Tissue Culture
- Transdifferentiation
- Clinical Trials
- Clinical Trials Outside U.S.: Amyotrophic Lateral Sclerosis
- Clinical Trials Outside U.S.: Avascular Necrosis
- Clinical Trials Outside U.S.: Severe Coronary Artery Disease
- Clinical Trials Outside U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Batten Disease
- Clinical Trials Within U.S.: Blind Process
- Clinical Trials Within U.S.: Cancer
- Clinical Trials Within U.S.: Heart Disease
- Clinical Trials Within U.S.: Peripheral Vascular Disease
- Clinical Trials Within U.S.: Skin Transplants (Burns)
- Clinical Trials Within U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Traumatic Brain Injury
- Clinical Trials Worldwide
- Countries
- Diseases
- Ethics
- History and Technology
- Birth Dating of Cells by Retrovirus
- Bone Marrow Transplants
- BrdU/Thymidine
- Fluorescence—Activated Cell Sorting
- Human Embryonic Stem Cells
- In Vitro Fertilization
- Mouse ES Cell Isolation
- MRI Tracking
- Non—Human Primate Embryonic Stem Cells
- Nuclear Transfer, Altered
- Nuclear Transfer, Somatic
- Parthogenesis
- Preimplantation Genetic Diagnosis
- Viral Vectors: Adeno—Associated Virus
- Viral Vectors: Adenovirus
- Viral Vectors: Lentivirus
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- Baylor College of Medicine
- Bonn University
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- Weill—Cornell Medical College
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- Legal Issues
- Organizations
- American Association for the Advancement of Science
- Australian Stem Cell Centre
- California Institute for Regenerative Medicine
- Canadian Stem Cell Network
- China Stem Cell News
- Christopher Reeve Foundation
- Community of Stem Cell Scientists
- Danish Stem Cell Research Center
- East of England Stem Cell Network
- European Consortium for Stem Cell Research—EuroStemCell
- International Society for Stem Cell Research
- International Stem Cell Forum
- Japan Human Cell Society
- Lasker Foundation
- Medical Research Council UK Stem Cell Initiative
- Michael J. Fox Foundation
- National Institutes of Health
- National Stem Cell Bank
- Parkinson's Disease Foundation
- Scottish Stem Cell Network
- Stem Cell Genome Anatomy Projects
- Swiss Stem Cell Network
- UK National Stem Cell Network
- Wisconsin Alumni Research Foundation
- People
- Alvarez—Buylla, Arturo
- Anversa, Piero
- Charo, Robin Alta
- Eaves, Connie
- Eggan, Kevin
- Fuchs, Elaine
- Gage, Fred
- Gearhart, John
- Goldman, Steven A.
- Jaenisch, Rudolf
- Keller, Gordon
- Kriegstein, Arnold
- Lanza, Robert
- Losordo, Douglas
- Macklis, Jeffrey
- McKay, Ronald D. G.
- Melton, Doug
- Morrison, Sean
- Mummery, Christine
- Nottebohm, Fernando
- Okano, Hideyuki
- Orkin, Stuart
- Rao, Mahendra
- Smith, Austin
- Snyder, Evan
- Steindler, Dennis A.
- Studer, Lorenz P.
- Thomson, James
- Van der Kooy, Derek
- Verfaillie, Catherine
- Vescovi, Angelo
- Weissman, Irving
- Wilmut, Ian
- Politics
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