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IN ACCORDANCE WITH its long history of cutting—edge medical care, the Mayo Clinic is now a leader in clinical research trials using stem cells for the treatment of human illness. The combination of patient care, medical education, and research ensures translation of basic research into patient therapies. Throughout its history, the Mayo Clinic has attracted medical professionals who have focused on improving medical practice and treatment. Some innovations initiated at the clinic have become global standards of practice, including medical charting and intramural communications. Medical research at the clinic began in 1907 with the establishment of research and diagnostic laboratories.

The Mayo Clinic is located in Rochester, Minnesota, with centers in Jacksonville, Florida, and Scottsdale, Arizona. All the centers provide identical clinical services and coordinated research. The founding clinic in Rochester grew from the medical practices of D. William W. Mayo and his two sons William J. Mayo and Charles Mayo. Recognizing the need for a hospital in Rochester after the devastating tornado of 1883, they, along with the Sisters of St. Francis, opened St. Mary's hospital in 1889; this hospital became part of the Mayo Clinic in 1986.

In 1919, a partnership of physicians, including the Mayos, created a not—for-profit association called the Mayo Properties Association, and the Mayos donated the clinic properties and equipment to this association. The Mayo Clinic provided $2 million for the founding of a medical school at the University of Minnesota in 1917. Physicians at the Mayo Clinic also taught at the medical school until the Mayo Clinic opened its own medical school in 1972.

In 1983, the Mayo Clinic began publishing health information targeted at consumers/patients through newsletters, books, and Internet content. The revenue from their publishing endeavors is used to support Mayo Clinic programs including medical education and research.

Education

The Mayo Medical School is an independent, degree—granting institution focusing on small class size in relation to faculty size for promoting enhanced patient care, and on clinical research, as well as graduate medical education and residencies in a variety of specialties, and accredited Continuing Medical Education to help physicians and other health professionals to keep current on skills and knowledge.

The Mayo School of Health Sciences focuses on educating allied health professionals. The school offers training to nurses and in a wide range of clinical support services, including laboratory, imaging, therapy, research, and pharmacy services. The Mayo Graduate School focuses on education and research opportunities in the biomédical sciences including virology, immunology, molecular biology, pharmacology, and related academic disciplines focused on improving the understanding and treatment of human disease.

Stem Cell Treatment

Stem cell transplants at the Mayo Clinic are performed by the blood and marrow transplant team, who have specialties in oncology and hematology as well as diverse other specialties. The transplant may be autologous (stem cells are collected from the patient for storage and reinfusion) or allogenic (cells are obtained from a relative or unrelated compatible donor) and are available to adult and children for a variety of diseases.

The Mayo Clinic offers stem cell treatment to adults for amyloidosis, aplastic anemia, genetic—kinked cancers (leukemias, lymphoma, multiple myeloma, and myelodysplastic syndrome), and solid tumors (ovarian, testicular, and brain). The treatment is also offered for children and adolescents for adrenoleukodystrophy, anemias (aplastic, Fanconi's, and sickle cell), leukemias, lymphomas, and some brain tumors, as well as solid tumors and some genetic—linked diseases.

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