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Mayo Clinic
IN ACCORDANCE WITH its long history of cutting—edge medical care, the Mayo Clinic is now a leader in clinical research trials using stem cells for the treatment of human illness. The combination of patient care, medical education, and research ensures translation of basic research into patient therapies. Throughout its history, the Mayo Clinic has attracted medical professionals who have focused on improving medical practice and treatment. Some innovations initiated at the clinic have become global standards of practice, including medical charting and intramural communications. Medical research at the clinic began in 1907 with the establishment of research and diagnostic laboratories.
The Mayo Clinic is located in Rochester, Minnesota, with centers in Jacksonville, Florida, and Scottsdale, Arizona. All the centers provide identical clinical services and coordinated research. The founding clinic in Rochester grew from the medical practices of D. William W. Mayo and his two sons William J. Mayo and Charles Mayo. Recognizing the need for a hospital in Rochester after the devastating tornado of 1883, they, along with the Sisters of St. Francis, opened St. Mary's hospital in 1889; this hospital became part of the Mayo Clinic in 1986.
In 1919, a partnership of physicians, including the Mayos, created a not—for-profit association called the Mayo Properties Association, and the Mayos donated the clinic properties and equipment to this association. The Mayo Clinic provided $2 million for the founding of a medical school at the University of Minnesota in 1917. Physicians at the Mayo Clinic also taught at the medical school until the Mayo Clinic opened its own medical school in 1972.
In 1983, the Mayo Clinic began publishing health information targeted at consumers/patients through newsletters, books, and Internet content. The revenue from their publishing endeavors is used to support Mayo Clinic programs including medical education and research.
Education
The Mayo Medical School is an independent, degree—granting institution focusing on small class size in relation to faculty size for promoting enhanced patient care, and on clinical research, as well as graduate medical education and residencies in a variety of specialties, and accredited Continuing Medical Education to help physicians and other health professionals to keep current on skills and knowledge.
The Mayo School of Health Sciences focuses on educating allied health professionals. The school offers training to nurses and in a wide range of clinical support services, including laboratory, imaging, therapy, research, and pharmacy services. The Mayo Graduate School focuses on education and research opportunities in the biomédical sciences including virology, immunology, molecular biology, pharmacology, and related academic disciplines focused on improving the understanding and treatment of human disease.
Stem Cell Treatment
Stem cell transplants at the Mayo Clinic are performed by the blood and marrow transplant team, who have specialties in oncology and hematology as well as diverse other specialties. The transplant may be autologous (stem cells are collected from the patient for storage and reinfusion) or allogenic (cells are obtained from a relative or unrelated compatible donor) and are available to adult and children for a variety of diseases.
The Mayo Clinic offers stem cell treatment to adults for amyloidosis, aplastic anemia, genetic—kinked cancers (leukemias, lymphoma, multiple myeloma, and myelodysplastic syndrome), and solid tumors (ovarian, testicular, and brain). The treatment is also offered for children and adolescents for adrenoleukodystrophy, anemias (aplastic, Fanconi's, and sickle cell), leukemias, lymphomas, and some brain tumors, as well as solid tumors and some genetic—linked diseases.
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- Biology
- Biotechnology, History of
- Cell Sorting
- Cells, Adult
- Cells, Amniotic
- Cells, Developing
- Cells, Embryonic
- Cells, Fetal
- Cells, Human
- Cells, Monkey
- Cells, Mouse (Embryonic)
- Cells, Neural
- Cells, Sources of
- Cells, Umbilical
- Cytogenetic Instability of Stem Cells
- Developmental Biology
- Differentiation, In Vitro and In Vivo
- Division Types (Symmetrical and Asymmetrical)
- Experimental Models
- Feeder/Feeder—Free Culture
- Gut Stem Cells
- Induced Pluripotent Stem Cells
- Lineages
- Mammary Stem Cells
- Markers of Sternness
- Methods of Growing Cells
- Microenvironment and Immune Issues
- Neuralstem
- Neurosphere Cultures
- Niche Self—Renewal
- Nuclear Reprogramming
- Parthogenesis
- Plant Stem Cells
- Prostate Tissue Stem Cells
- Renal Stem Cells
- Self—Renewal, Stem Cell
- Stem Cell Applications, Articular Cartilage
- Stem Cell Applications, Tendon and Ligament
- Stem—Like Cells, Human Brain
- Tissue Culture
- Transdifferentiation
- Clinical Trials
- Clinical Trials Outside U.S.: Amyotrophic Lateral Sclerosis
- Clinical Trials Outside U.S.: Avascular Necrosis
- Clinical Trials Outside U.S.: Severe Coronary Artery Disease
- Clinical Trials Outside U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Batten Disease
- Clinical Trials Within U.S.: Blind Process
- Clinical Trials Within U.S.: Cancer
- Clinical Trials Within U.S.: Heart Disease
- Clinical Trials Within U.S.: Peripheral Vascular Disease
- Clinical Trials Within U.S.: Skin Transplants (Burns)
- Clinical Trials Within U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Traumatic Brain Injury
- Clinical Trials Worldwide
- Countries
- Diseases
- Ethics
- History and Technology
- Birth Dating of Cells by Retrovirus
- Bone Marrow Transplants
- BrdU/Thymidine
- Fluorescence—Activated Cell Sorting
- Human Embryonic Stem Cells
- In Vitro Fertilization
- Mouse ES Cell Isolation
- MRI Tracking
- Non—Human Primate Embryonic Stem Cells
- Nuclear Transfer, Altered
- Nuclear Transfer, Somatic
- Parthogenesis
- Preimplantation Genetic Diagnosis
- Viral Vectors: Adeno—Associated Virus
- Viral Vectors: Adenovirus
- Viral Vectors: Lentivirus
- Industry
- Institutions
- Albert Einstein College of Medicine
- Baylor College of Medicine
- Bonn University
- Burnham Institute
- Caltech
- Cambridge University
- Case Western Reserve University/Cleveland Clinic
- Children's Hospital, Boston
- Columbia University
- Coriell Institute
- Duke University
- Genetics Policy Institute
- Harvard University
- Indiana University
- Johns Hopkins University
- Kyoto University
- Massachusetts General Hospital
- Massachusetts Institute of Technology
- Mayo Clinic
- McMaster University
- Mount Sinai School of Medicine
- National Academy of Science
- Northwestern University
- Oregon Health & Science University
- Ottawa Health Research Institute
- Oxford University
- Princeton University
- Reeve—Irvine Research Center
- Robarts Research Institute
- Rockefeller University
- Rutgers University
- Salk Institute
- Scripps Research Institute
- Sloan—Kettering Institute
- Stanford University
- Stowers Institute
- University of California, Berkeley
- University of California, Davis
- University of California, Los Angeles
- University of California, San Diego
- University of California, San Francisco
- University of Connecticut
- University of Georgia
- University of Miami
- University of Michigan
- University of Minnesota
- University of North Carolina, Chapel Hill
- University of Pittsburgh
- University of Southern California
- University of Texas Health Science Center at Houston
- University of Toronto
- University of Washington/Hutchinson Cancer Center
- University of Wisconsin, Madison
- Vanderbilt of University
- Wake Forest University
- Weill—Cornell Medical College
- Whitehead Institute
- Yale University
- Legal Issues
- Organizations
- American Association for the Advancement of Science
- Australian Stem Cell Centre
- California Institute for Regenerative Medicine
- Canadian Stem Cell Network
- China Stem Cell News
- Christopher Reeve Foundation
- Community of Stem Cell Scientists
- Danish Stem Cell Research Center
- East of England Stem Cell Network
- European Consortium for Stem Cell Research—EuroStemCell
- International Society for Stem Cell Research
- International Stem Cell Forum
- Japan Human Cell Society
- Lasker Foundation
- Medical Research Council UK Stem Cell Initiative
- Michael J. Fox Foundation
- National Institutes of Health
- National Stem Cell Bank
- Parkinson's Disease Foundation
- Scottish Stem Cell Network
- Stem Cell Genome Anatomy Projects
- Swiss Stem Cell Network
- UK National Stem Cell Network
- Wisconsin Alumni Research Foundation
- People
- Alvarez—Buylla, Arturo
- Anversa, Piero
- Charo, Robin Alta
- Eaves, Connie
- Eggan, Kevin
- Fuchs, Elaine
- Gage, Fred
- Gearhart, John
- Goldman, Steven A.
- Jaenisch, Rudolf
- Keller, Gordon
- Kriegstein, Arnold
- Lanza, Robert
- Losordo, Douglas
- Macklis, Jeffrey
- McKay, Ronald D. G.
- Melton, Doug
- Morrison, Sean
- Mummery, Christine
- Nottebohm, Fernando
- Okano, Hideyuki
- Orkin, Stuart
- Rao, Mahendra
- Smith, Austin
- Snyder, Evan
- Steindler, Dennis A.
- Studer, Lorenz P.
- Thomson, James
- Van der Kooy, Derek
- Verfaillie, Catherine
- Vescovi, Angelo
- Weissman, Irving
- Wilmut, Ian
- Politics
- Advocacy
- Coalition for the Advancement of Medical Research
- Congress: Votes and Amendments (Cloning/Embryos)
- Dickey Amendment
- Do No Harm: The Coalition of Americans for Research Ethics
- National Right to Life Committee
- President's Council on Bioethics
- Presidential Campaigns
- Reagan, Nancy
- Special Interest/Lobby Groups
- Stem Cells, Bush Ruling
- Religion
- States
- Alabama
- Arizona
- Arkansas
- California
- Colorado
- Connecticut
- Delaware
- Florida
- Georgia
- Hawaii
- Idaho
- Illinois
- Indiana
- Iowa
- Kansas
- Kentucky
- Louisiana
- Maine
- Maryland
- Massachusetts
- Michigan
- Minnesota
- Mississippi
- Missouri
- Montana
- Nebraska
- Nevada
- New Hampshire
- New Jersey
- New Mexico
- New York
- North Carolina
- North Dakota
- Ohio
- Oklahoma
- Oregon
- Pennsylvania
- Rhode Island
- South Carolina
- South Dakota
- Tennessee
- Texas
- Utah
- Vermont
- Virginia
- Washington
- West Virginia
- Wisconsin
- Wyoming
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