Entry
Reader's guide
Entries A-Z
Subject index
Harvard University
HARVARD UNIVERSITY, FOUNDED in 1636, is a private university located in Cambridge, Massachusetts, and is the oldest institution of higher learning in the United States. It is a member of the Ivy League. Recently, Harvard University opened the Harvard Stem Cell Institute (HSCI), a body committed to translating stem cell research in the laboratory into the clinic as quickly as possible in an attempt to treat disease. Harvard supports research primarily in developing new therapies for disease (e.g., diabetes, cardiovascular disease, and cancer). In fact, HSCI identifies itself as a “scientific collaborative established to fulfill the promise of stem cell biology as the basis for cures and treatments for a wide range of chronic medical conditions.” HSCI states that at present, no embryonic stem cells (ES) have been used to treat diseases in humans, although research on these ES shows great potential. “Stem cell—based therapies are already in widespread clinical use, in the form of bone marrow and cord blood transplants.”
The Harvard community consists of the university, the medical school, and 18 research institutions and hospitals, making it one of the world's largest concentrations of biomédical researchers. HSCI is aware of the importance of interdisci—plinarity in this novel field of science; therefore, it is devoted to the virtue of community. HSCI works closely with its allies: Beth Israel Deaconess Medical Center, Howard Hughes Medical Institute, Brigham and Women's Hospital, Massachusetts General Hospital, Children's Hospital Boston, Joslin Diabetes Center, the Forsyth Institute, McLean Hospital, the Schepens Eye Research Institute, and the Immune Disease Institute, among other institutions from around the world. Harvard also incorporates nearly every department into its stem cell research: the John F. Kennedy School of Government, Harvard School of Public Health, Harvard Law School, Harvard Divinity School, Harvard Business School, Harvard Medical School, Radcliffe Institute for Advanced Study, and Harvard University.
HSCI states that it is currently “supported primarily by private philanthropic donations,” which allows it to support a spectrum of research activities that could not otherwise be supported by sources such as the National Institutes of Health. The HSCI has created a unique fusion of professional institutions to address societal issues regarding stem cell research, ranging from legal and political issues to economic and ethical concerns; this interdisciplinary approach has permitted a unique synthesis of the institution's resources and its collaborators.
Programs
As of October 2007, HSCI focuses on basic research and clinical translation in five principal disease areas: cancer, diabetes, nervous system diseases, blood diseases, and cardiovascular disease. Studies suggest that
In the United States alone it has been estimated that as many as 100 million people suffer from diseases that could be amenable to stem cell—based therapies.
As a consequence, the mission of HSCI is to encompass basic research on all aspects of stem cell biology, with an emphasis on improving human health. In addition to the five major disease areas listed here, faculty members at HSCI have expanded their works to include research in muscle, kidney, skin, reproductive, and liver and gastrointestinal tract diseases.
HSCI has training opportunities for nearly all members of the academic community: undergraduates, graduates, and postdoctoral students. Undergraduate students interested in gaining laboratory experience may review the principal investigators' and faculty members' profiles to determine in which laboratory he or she would like to work; students are then encouraged to inquire directly to those researchers. An undergraduate summer research intern program is also available for students who are interested in participating in stem cell research in an HSCI—affiliated laboratory.
...
- Biology
- Biotechnology, History of
- Cell Sorting
- Cells, Adult
- Cells, Amniotic
- Cells, Developing
- Cells, Embryonic
- Cells, Fetal
- Cells, Human
- Cells, Monkey
- Cells, Mouse (Embryonic)
- Cells, Neural
- Cells, Sources of
- Cells, Umbilical
- Cytogenetic Instability of Stem Cells
- Developmental Biology
- Differentiation, In Vitro and In Vivo
- Division Types (Symmetrical and Asymmetrical)
- Experimental Models
- Feeder/Feeder—Free Culture
- Gut Stem Cells
- Induced Pluripotent Stem Cells
- Lineages
- Mammary Stem Cells
- Markers of Sternness
- Methods of Growing Cells
- Microenvironment and Immune Issues
- Neuralstem
- Neurosphere Cultures
- Niche Self—Renewal
- Nuclear Reprogramming
- Parthogenesis
- Plant Stem Cells
- Prostate Tissue Stem Cells
- Renal Stem Cells
- Self—Renewal, Stem Cell
- Stem Cell Applications, Articular Cartilage
- Stem Cell Applications, Tendon and Ligament
- Stem—Like Cells, Human Brain
- Tissue Culture
- Transdifferentiation
- Clinical Trials
- Clinical Trials Outside U.S.: Amyotrophic Lateral Sclerosis
- Clinical Trials Outside U.S.: Avascular Necrosis
- Clinical Trials Outside U.S.: Severe Coronary Artery Disease
- Clinical Trials Outside U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Batten Disease
- Clinical Trials Within U.S.: Blind Process
- Clinical Trials Within U.S.: Cancer
- Clinical Trials Within U.S.: Heart Disease
- Clinical Trials Within U.S.: Peripheral Vascular Disease
- Clinical Trials Within U.S.: Skin Transplants (Burns)
- Clinical Trials Within U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Traumatic Brain Injury
- Clinical Trials Worldwide
- Countries
- Diseases
- Ethics
- History and Technology
- Birth Dating of Cells by Retrovirus
- Bone Marrow Transplants
- BrdU/Thymidine
- Fluorescence—Activated Cell Sorting
- Human Embryonic Stem Cells
- In Vitro Fertilization
- Mouse ES Cell Isolation
- MRI Tracking
- Non—Human Primate Embryonic Stem Cells
- Nuclear Transfer, Altered
- Nuclear Transfer, Somatic
- Parthogenesis
- Preimplantation Genetic Diagnosis
- Viral Vectors: Adeno—Associated Virus
- Viral Vectors: Adenovirus
- Viral Vectors: Lentivirus
- Industry
- Institutions
- Albert Einstein College of Medicine
- Baylor College of Medicine
- Bonn University
- Burnham Institute
- Caltech
- Cambridge University
- Case Western Reserve University/Cleveland Clinic
- Children's Hospital, Boston
- Columbia University
- Coriell Institute
- Duke University
- Genetics Policy Institute
- Harvard University
- Indiana University
- Johns Hopkins University
- Kyoto University
- Massachusetts General Hospital
- Massachusetts Institute of Technology
- Mayo Clinic
- McMaster University
- Mount Sinai School of Medicine
- National Academy of Science
- Northwestern University
- Oregon Health & Science University
- Ottawa Health Research Institute
- Oxford University
- Princeton University
- Reeve—Irvine Research Center
- Robarts Research Institute
- Rockefeller University
- Rutgers University
- Salk Institute
- Scripps Research Institute
- Sloan—Kettering Institute
- Stanford University
- Stowers Institute
- University of California, Berkeley
- University of California, Davis
- University of California, Los Angeles
- University of California, San Diego
- University of California, San Francisco
- University of Connecticut
- University of Georgia
- University of Miami
- University of Michigan
- University of Minnesota
- University of North Carolina, Chapel Hill
- University of Pittsburgh
- University of Southern California
- University of Texas Health Science Center at Houston
- University of Toronto
- University of Washington/Hutchinson Cancer Center
- University of Wisconsin, Madison
- Vanderbilt of University
- Wake Forest University
- Weill—Cornell Medical College
- Whitehead Institute
- Yale University
- Legal Issues
- Organizations
- American Association for the Advancement of Science
- Australian Stem Cell Centre
- California Institute for Regenerative Medicine
- Canadian Stem Cell Network
- China Stem Cell News
- Christopher Reeve Foundation
- Community of Stem Cell Scientists
- Danish Stem Cell Research Center
- East of England Stem Cell Network
- European Consortium for Stem Cell Research—EuroStemCell
- International Society for Stem Cell Research
- International Stem Cell Forum
- Japan Human Cell Society
- Lasker Foundation
- Medical Research Council UK Stem Cell Initiative
- Michael J. Fox Foundation
- National Institutes of Health
- National Stem Cell Bank
- Parkinson's Disease Foundation
- Scottish Stem Cell Network
- Stem Cell Genome Anatomy Projects
- Swiss Stem Cell Network
- UK National Stem Cell Network
- Wisconsin Alumni Research Foundation
- People
- Alvarez—Buylla, Arturo
- Anversa, Piero
- Charo, Robin Alta
- Eaves, Connie
- Eggan, Kevin
- Fuchs, Elaine
- Gage, Fred
- Gearhart, John
- Goldman, Steven A.
- Jaenisch, Rudolf
- Keller, Gordon
- Kriegstein, Arnold
- Lanza, Robert
- Losordo, Douglas
- Macklis, Jeffrey
- McKay, Ronald D. G.
- Melton, Doug
- Morrison, Sean
- Mummery, Christine
- Nottebohm, Fernando
- Okano, Hideyuki
- Orkin, Stuart
- Rao, Mahendra
- Smith, Austin
- Snyder, Evan
- Steindler, Dennis A.
- Studer, Lorenz P.
- Thomson, James
- Van der Kooy, Derek
- Verfaillie, Catherine
- Vescovi, Angelo
- Weissman, Irving
- Wilmut, Ian
- Politics
- Advocacy
- Coalition for the Advancement of Medical Research
- Congress: Votes and Amendments (Cloning/Embryos)
- Dickey Amendment
- Do No Harm: The Coalition of Americans for Research Ethics
- National Right to Life Committee
- President's Council on Bioethics
- Presidential Campaigns
- Reagan, Nancy
- Special Interest/Lobby Groups
- Stem Cells, Bush Ruling
- Religion
- States
- Alabama
- Arizona
- Arkansas
- California
- Colorado
- Connecticut
- Delaware
- Florida
- Georgia
- Hawaii
- Idaho
- Illinois
- Indiana
- Iowa
- Kansas
- Kentucky
- Louisiana
- Maine
- Maryland
- Massachusetts
- Michigan
- Minnesota
- Mississippi
- Missouri
- Montana
- Nebraska
- Nevada
- New Hampshire
- New Jersey
- New Mexico
- New York
- North Carolina
- North Dakota
- Ohio
- Oklahoma
- Oregon
- Pennsylvania
- Rhode Island
- South Carolina
- South Dakota
- Tennessee
- Texas
- Utah
- Vermont
- Virginia
- Washington
- West Virginia
- Wisconsin
- Wyoming
- Loading...
Get a 30 day FREE TRIAL
-
Watch videos from a variety of sources bringing classroom topics to life
-
Read modern, diverse business cases
-
Explore hundreds of books and reference titles
Sage Recommends
We found other relevant content for you on other Sage platforms.
Have you created a personal profile? Login or create a profile so that you can save clips, playlists and searches