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Biotechnology, History of
THE 17TH CENTURY is seen as the most propitious era for scientific intervention. The period is often described as the century of genius, for most scientific leaps began in this era and continued well into the 18th century, only to be regrouped retrospectively in the early part of the 20th century. The invention of the telescope, the thermometer, and the barometer benefitted those countries at war. In addition, however, the scientific and philosophical interests that emerged at the time also stimulated productive thoughts and aspirations that were expressed in the latter part of the century. The period, thus, was marked by a very successful scientific revolution.
In France, Western Europe, and England, the period between Galileo's first publications and Newton's Principia was characterized by changes that altered the development of new technologies. The granting of patents in Florence and England constituted an important chapter in the history of technological inventions. The terms invention, inventor, and monopoly, and legalizing them, became significant with regard to technology.
Development of the science of mechanics and power technology marked yet another phase in the development of technological innovations in later years. Although the need to devise improved technology was a prominent feature of this innovation, there was a concomitant improvement in the way new technology was put to practical use for the benefit of mankind. What was more important was how these new technologies fitted into the need of the society in terms of reliability, economic viability, and the felt need of the community at large.
Amid new technology, an important factor that influenced its practical application was the rise of a unanimous sense of reasoning and logic of progress. This led to the establishment of technological institutions that were directly supported by the state. France and Britain became active recipients of this institutional progress. Although, initially, the need to have such set—ups came from the army and civil services, it was not long before their relevance was recognized in making technology completely autonomous and open to the public. In England, advanced technology in terms of railroad networks and bridges reflected the rise of a specific technological profession—that of engineering. Gradually, moving into the 18th and 19th centuries, there is a continuous expansion of mining and textile industries that benefitted greatly from the new technologies.
It was not until the first half of the 19th century that science as a profession, per se, was organized on sound basis into a definite structure that also continued in later years. New scientific paradigms were created to cater to the needs of the expanding scientific horizons. Thus began new ideas of introducing electro—technology and of improved concepts of power. Much of the 19th century gave hope of successful technological progress. Some of these successes were used in war situations; for example, the invention of the Bessemer steel—making process by Henry Bessemer (1813–98). Bessemer invented new designs for heavy guns using new and cost—effective methods of manufacturing them.

In the past 30 years, Western scientists have used the term biotechnology to refer to laboratory—based techniques.
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- Biology
- Biotechnology, History of
- Cell Sorting
- Cells, Adult
- Cells, Amniotic
- Cells, Developing
- Cells, Embryonic
- Cells, Fetal
- Cells, Human
- Cells, Monkey
- Cells, Mouse (Embryonic)
- Cells, Neural
- Cells, Sources of
- Cells, Umbilical
- Cytogenetic Instability of Stem Cells
- Developmental Biology
- Differentiation, In Vitro and In Vivo
- Division Types (Symmetrical and Asymmetrical)
- Experimental Models
- Feeder/Feeder—Free Culture
- Gut Stem Cells
- Induced Pluripotent Stem Cells
- Lineages
- Mammary Stem Cells
- Markers of Sternness
- Methods of Growing Cells
- Microenvironment and Immune Issues
- Neuralstem
- Neurosphere Cultures
- Niche Self—Renewal
- Nuclear Reprogramming
- Parthogenesis
- Plant Stem Cells
- Prostate Tissue Stem Cells
- Renal Stem Cells
- Self—Renewal, Stem Cell
- Stem Cell Applications, Articular Cartilage
- Stem Cell Applications, Tendon and Ligament
- Stem—Like Cells, Human Brain
- Tissue Culture
- Transdifferentiation
- Clinical Trials
- Clinical Trials Outside U.S.: Amyotrophic Lateral Sclerosis
- Clinical Trials Outside U.S.: Avascular Necrosis
- Clinical Trials Outside U.S.: Severe Coronary Artery Disease
- Clinical Trials Outside U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Batten Disease
- Clinical Trials Within U.S.: Blind Process
- Clinical Trials Within U.S.: Cancer
- Clinical Trials Within U.S.: Heart Disease
- Clinical Trials Within U.S.: Peripheral Vascular Disease
- Clinical Trials Within U.S.: Skin Transplants (Burns)
- Clinical Trials Within U.S.: Spinal Cord Injury
- Clinical Trials Within U.S.: Traumatic Brain Injury
- Clinical Trials Worldwide
- Countries
- Diseases
- Ethics
- History and Technology
- Birth Dating of Cells by Retrovirus
- Bone Marrow Transplants
- BrdU/Thymidine
- Fluorescence—Activated Cell Sorting
- Human Embryonic Stem Cells
- In Vitro Fertilization
- Mouse ES Cell Isolation
- MRI Tracking
- Non—Human Primate Embryonic Stem Cells
- Nuclear Transfer, Altered
- Nuclear Transfer, Somatic
- Parthogenesis
- Preimplantation Genetic Diagnosis
- Viral Vectors: Adeno—Associated Virus
- Viral Vectors: Adenovirus
- Viral Vectors: Lentivirus
- Industry
- Institutions
- Albert Einstein College of Medicine
- Baylor College of Medicine
- Bonn University
- Burnham Institute
- Caltech
- Cambridge University
- Case Western Reserve University/Cleveland Clinic
- Children's Hospital, Boston
- Columbia University
- Coriell Institute
- Duke University
- Genetics Policy Institute
- Harvard University
- Indiana University
- Johns Hopkins University
- Kyoto University
- Massachusetts General Hospital
- Massachusetts Institute of Technology
- Mayo Clinic
- McMaster University
- Mount Sinai School of Medicine
- National Academy of Science
- Northwestern University
- Oregon Health & Science University
- Ottawa Health Research Institute
- Oxford University
- Princeton University
- Reeve—Irvine Research Center
- Robarts Research Institute
- Rockefeller University
- Rutgers University
- Salk Institute
- Scripps Research Institute
- Sloan—Kettering Institute
- Stanford University
- Stowers Institute
- University of California, Berkeley
- University of California, Davis
- University of California, Los Angeles
- University of California, San Diego
- University of California, San Francisco
- University of Connecticut
- University of Georgia
- University of Miami
- University of Michigan
- University of Minnesota
- University of North Carolina, Chapel Hill
- University of Pittsburgh
- University of Southern California
- University of Texas Health Science Center at Houston
- University of Toronto
- University of Washington/Hutchinson Cancer Center
- University of Wisconsin, Madison
- Vanderbilt of University
- Wake Forest University
- Weill—Cornell Medical College
- Whitehead Institute
- Yale University
- Legal Issues
- Organizations
- American Association for the Advancement of Science
- Australian Stem Cell Centre
- California Institute for Regenerative Medicine
- Canadian Stem Cell Network
- China Stem Cell News
- Christopher Reeve Foundation
- Community of Stem Cell Scientists
- Danish Stem Cell Research Center
- East of England Stem Cell Network
- European Consortium for Stem Cell Research—EuroStemCell
- International Society for Stem Cell Research
- International Stem Cell Forum
- Japan Human Cell Society
- Lasker Foundation
- Medical Research Council UK Stem Cell Initiative
- Michael J. Fox Foundation
- National Institutes of Health
- National Stem Cell Bank
- Parkinson's Disease Foundation
- Scottish Stem Cell Network
- Stem Cell Genome Anatomy Projects
- Swiss Stem Cell Network
- UK National Stem Cell Network
- Wisconsin Alumni Research Foundation
- People
- Alvarez—Buylla, Arturo
- Anversa, Piero
- Charo, Robin Alta
- Eaves, Connie
- Eggan, Kevin
- Fuchs, Elaine
- Gage, Fred
- Gearhart, John
- Goldman, Steven A.
- Jaenisch, Rudolf
- Keller, Gordon
- Kriegstein, Arnold
- Lanza, Robert
- Losordo, Douglas
- Macklis, Jeffrey
- McKay, Ronald D. G.
- Melton, Doug
- Morrison, Sean
- Mummery, Christine
- Nottebohm, Fernando
- Okano, Hideyuki
- Orkin, Stuart
- Rao, Mahendra
- Smith, Austin
- Snyder, Evan
- Steindler, Dennis A.
- Studer, Lorenz P.
- Thomson, James
- Van der Kooy, Derek
- Verfaillie, Catherine
- Vescovi, Angelo
- Weissman, Irving
- Wilmut, Ian
- Politics
- Advocacy
- Coalition for the Advancement of Medical Research
- Congress: Votes and Amendments (Cloning/Embryos)
- Dickey Amendment
- Do No Harm: The Coalition of Americans for Research Ethics
- National Right to Life Committee
- President's Council on Bioethics
- Presidential Campaigns
- Reagan, Nancy
- Special Interest/Lobby Groups
- Stem Cells, Bush Ruling
- Religion
- States
- Alabama
- Arizona
- Arkansas
- California
- Colorado
- Connecticut
- Delaware
- Florida
- Georgia
- Hawaii
- Idaho
- Illinois
- Indiana
- Iowa
- Kansas
- Kentucky
- Louisiana
- Maine
- Maryland
- Massachusetts
- Michigan
- Minnesota
- Mississippi
- Missouri
- Montana
- Nebraska
- Nevada
- New Hampshire
- New Jersey
- New Mexico
- New York
- North Carolina
- North Dakota
- Ohio
- Oklahoma
- Oregon
- Pennsylvania
- Rhode Island
- South Carolina
- South Dakota
- Tennessee
- Texas
- Utah
- Vermont
- Virginia
- Washington
- West Virginia
- Wisconsin
- Wyoming
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