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Propensity Score Analysis

Propensity score analysis is a technique for estimating the causal effect of a treatment in an observational study. Although randomized experiments are the ideal method for estimating the causal effect of a treatmentbecause randomization ensures that, on average, the distribution of both observed and unobserved characteristics are the same for treated and untreated unitsthere are many cases where randomized experiments are unethical or impractical. In an observational study, unlike in a randomized experiment, the researcher has no control over treatment assignment. As a result, due to self-selection into treatment or other nonrandom aspects of the treatment assignment, there may be systematic differences between the treated and control groups that can bias the estimate of treatment effects. Using propensity scores to match treated units to similar control units is one way to adjust for observed differences between the two groups and thereby reduce this selection bias in the treatment effect estimate. Bias may not be completely eliminated because propensity score analysis will not adjust for unobserved differences between the two groups, except to the extent that observed variables are correlated with these unobserved variables; however, this is a limitation of any nonrandomized study.

This entry describes the theory underlying this analysis. Next, the entry presents the steps involved in implementing propensity score analysis. The entry concludes with a brief discussion of alternate uses for propensity scores.

Underlying Theory

Formally, the propensity score is defined as the conditional probability of receiving treatment given a set of observed covariates. For simplicity, treatment will be assumed to be a binary variable (i.e., treatment or control). The majority of propensity score research addresses this binary treatment case; however, the propensity score method has been extended to treatments with multiple doses. The propensity score is a one-number summary of the multivariate information in the covariates that are related to treatment assignment. More specifically, the propensity score is a balancing score in the sense that matching on the propensity score creates pairs or subclasses within which the distribution of observed covariates is the same, on average, for both treated and control groups. In other words, the covariate distributions are “balanced” between the treated and control groups within these subclasses. Under two key assumptionsstrongly ignorable treatment assignment and stable unit treatment value assumption (SUTVA)an unbiased estimate of the average treatment effect at a specific propensity score value is given by the difference between the treated and control means for all units with that value of the propensity score. Averaging these differences across all propensity score values in the population yields an average overall treatment effect. The strongly ignorable treatment assumption implies that each unit has a nonzero probability of receiving treatment and that all relevant covariates have been included in the propensity score model so that treatment assignment is unconfounded with the covariates (sometimes referred to as “unconfoundedness” or “no hidden bias” or “selection on observables”). The SUTVA assumption implies that there is only one version of each treatment for each unit and that the treatment assignment of one unit does not affect the outcome of any other units (“no interference between units”).

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