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Center for Biological and Environmental Nanotechnology

Public policy with regard to nanotechnology has at times been curiously bifurcated. To a first approximation, policy for nano has been directed largely toward establishing interdisciplinary centers to aid university-industry cooperation in electronics and, increasingly, medicine. Policy debates about nanotechnology, on the other hand, have largely revolved around potential risks to health and the environment, and public perceptions of those risks. One of the first and most important institutions at the intersection of policy for and policy about nano is the Center for Biological and Environmental Nanotechnology (CBEN) at Rice University.

CBEN was the product of a convergence of two coalitions in the late 1990s, one local to Rice and one national in scope but located largely at the U.S. National Science Foundation (NSF) and the U.S. National Nanotechnology Initiative (NNI). Two key figures mediated between these coalitions: Richard Smalley, the Nobel laureate chemist and codiscoverer of the buckyball; and Neal Lane, a physicist, former Rice provost and NSF director, then science advisor to President Bill Clinton. Over the course of his career, Smalley built up a large institutional base for nanotechnology at Rice, encompassing more than a quarter of the school's science and engineering faculty. He did so initially through his directorship of the Rice Quantum Institute, then by founding the Center for Nanoscale Science and Technology (CNST) in the mid-1990s. Smalley's vision for what nanotechnology would be—a convergence of science and engineering and a catalyst for commercialization of academic research—clearly informed Lane's support for efforts to build a National Nanotechnology Initiative. In addition, Smalley had a large presence on the national science policy scene, and his CNST was taken as a model for the first round of Nanoscale Science and Engineering Centers funded by the NSF.

By the late 1990s, Smalley hoped to get NSF funding for a Center for Carbon Nanotechnology at Rice. This proposal was turned down, however, partly because reviewers felt it would take Smalley away from his research. So when two younger Rice faculty, Vicki Colvin and Mark Wiesner, presented a proposal to run a Center for Biological and Environmental Nanotechnology, Smalley became its champion.

The Good, the Bad, and the Ugly

Smalley's vision for CBEN differed somewhat from Colvin and Wiesner's, however. Smalley wanted a center focused on molecular electronics or nanoelectronic devices, for which he was recruiting faculty such as James Tour. Colvin, who had initially become interested in a Center as a way to bring expensive instrumentation such as a transmission electron microscope to Rice, thought that other universities were too far ahead of Rice in electronics, but that Rice's reputation in environmental and bioengineering was strong enough that a center proposal in that area would have a good chance.

This spurred Colvin to recruit Wiesner and other Rice engineers, such as Jennifer West, to join the CBEN proposal. Both Wiesner and West pointed out that, because of U.S. Federal Drug Administration (FDA) and U.S. Environmental Protection Agency (EPA) regulation, the toxicology and environmental impacts of any nanoparticles researched at CBEN would have to be understood for commercialization of that research to succeed. Wiesner, in particular, insisted that CBEN should make the potential impacts of nanotechnology a central focus, much to Smalley's dismay. Smalley, meanwhile, insisted that CBEN focus on the “wet/dry interface,” that is, materials that combined biomolecules or biological systems with the crystals and inorganic molecules more often studied by materials scientists and device physicists.

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