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Fear and anxiety can alter decision making in a wide range of domains, not least of all decisions about one's own health or the health of patients under a physician's care. Past research has demonstrated this influence, including in medicine. Understanding the impact that these basic emotions have on medical decisions, particularly those involving risky and uncertain options, is essential to understanding medical decision making and building accurate predictive models of choice. Traditional economic models of decision making, such as expected utility theory, propose that patients and physicians weigh decision options rationally and choose an action based on the likelihood and the payoff of outcomes. These models rarely include psychological influences on behavior, particularly the emotional ones. In the medical context, an important omission from these models is the effect of patients' and physicians' emotions as they weigh the options associated with treating a serious medical condition and choose an action. Patients and physicians must consider the possible consequences of treatment decisions, and how likely these would be to occur. Decisions involving risky, uncertain outcomes are especially susceptible to the influence of emotions such as anxiety. Anxiety is common in patients with serious illness who must make risky treatment decisions with major consequences: death, functional disability, diminished quality of life and psychological well-being. Their fear and anxiety can significantly alter their decisions. Both patients and physicians can be affected by fear and anxiety when making these decisions.

Influence on Decision Making

Fear and anxiety are related emotions that can influence decision making in multiple ways. Two potential formulations for the role of anxiety are that (1) anxiety and fear about risks alter the evaluation process (such as probability assessments) and (2) anxiety and fear lead to seeking relief from the state. There appears to be a curvilinear relationship between escalating anxiety and performance. Under this conception, anxiety is emotional arousal, and it places a load on central cognitive processing, so that anxious decision makers evaluate evidence differently than nonanxious ones. At low levels, arousal can improve task performance, likely by recruiting additional cognitive resources, initiating coping strategies, and increasing motivation for success. However, when arousal becomes sufficiently high to be appreciable anxiety and fear, it then exceeds the cognitive analytic capacities and leads to greater use of problem simplification. This is most problematic if the decision maker has limited information, as many patients do, or if one has many complex problems and uncertain factors to consider, as many physicians do.

Additionally, immediate strong (negative) emotions (i.e., “hot states”) can overwhelm cognitive goals and affect the way future dispassionate risks (i.e., “cold states”) are evaluated. Initial, primitive reactions to personally relevant information consist of a rudimentary “good versus bad” interpretation. Fearful reactions to risk have been shown to cause decision making to diverge from cognitive-based assessments of risk. Anxiety is formulated as a psychic-physiologic state that one is highly motivated to alleviate and from which one wishes to return to a nonanxious, or less anxious, baseline.

Influence on Medical Decision Making

In the field of medicine, anxious individuals make decisions to alleviate existing anxiety states as well as to avoid new situations that cause anxiety. Although statistical odds might indicate that continuing watchful waiting, in lieu of initiating a risky treatment, is advisable at an early stage of a disease, patients and physicians may fear the consequences of not treating so acutely that the evidence-based statistical guidelines are overruled. Likewise, patients may avoid indicated treatment due to the anxiety that it evokes. Thomas Denberg and colleagues' investigation of men's treatment choices for localized prostate cancer yielded many cases where patients considered risky surgery as “dreadful” and associated with likely death.

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