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Genetic engineering is a catchall term for the development of substantially novel living organisms and marks a breakthrough from selective breeding or conventional hybridization that has gone on without controversy for centuries. In its most common form, genetic engineering describes the direct transfer of genetic material across or within an organism's genome, which is then described as a “transgenic organism,” “genetically engineered” (GE) organism, or a “genetically modified organism” (GMO). GMOs breed true, while hybrids do not; the entire germ line of the modified organisms are permanently reconfigured. Scientists and private industry embrace transgenic modification because this allows the more precise insertion of genes carrying desired traits into target organisms. Genetic engineering is used in a variety of contexts. It has been relatively uncontroversial in medical applications such as human insulin and far more controversial as an agricultural technology.

To date, commercially grown genetically engineered organisms in agriculture have been limited to a few major grain and legume crops that function as industrial inputs for the modern food system and less effort into the manipulation of animals. The first wave of crop biotechnology emphasized traits to increase the economic efficiencies of large-scale farming. The two most common traits engineered into seeds are naturally occurring insecticides and tolerance to herbicides. The second wave is poised to deliver traits desirable for consumers, such as nutritional or health benefits. The third wave will bring factories to the fields in the form of crops that produce pharmaceuticals or industrial chemicals. From one perspective, it is merely the technological improvement on conventional plant breeding. But from another vantage, it poses the threat of serious ecological and social disruption. Genetic engineering is a highly controversial practice among some producers and consumers in industrialized nations, more so in Europe and Japan than in the United States. Its proponents regard it as a panacea for the world's food and environmental problems. But its critics charge that it will maintain worrying trends in industrial agriculture.

Its Endless Promise

Before any controversy started, growers of our most basic crops—corn, soybeans, cotton, canola—adopted GMOs, and for good reasons. Monsanto's Roundup Ready soybeans, corn, and canola (rapeseed), for instance, are engineered to be tolerant to Roundup, the most popular broad-spectrum herbicide on the market. These crops are planted extensively, in blocks of thousands of acres, allowing growers to spray herbicides directly over the crop—without affecting it—to kill weeds. Roundup Ready seeds simplify weed control. However, the technology user fees that accompany the patented seeds incur additional expenses that must be weighed against purported benefits. The potential for increased herbicide usage or the evolution of herbicide resistance in weeds also figure into the logic of adoption.

Corn (maize) and cotton genetically engineered with Bacillus thuringiensis (Bt), a naturally occurring soil bacterium that is lethal to the larvae of lepidopteran insects (butterfly and moth family, some of the most common agricultural pests), have other advantages. Bt is not toxic to humans or other animals, with the exception of this specific order of insects. Private industry has engineered Bt into crops to reduce reliance on insecticides, and GE crop has this naturally occurring pesticide in every cell. In small, targeted amounts, Bt has proven relatively environmentally safe; it has been used by organic gardeners and farmers for years, as a natural alternative to petroleum-based, chlorine-laced pesticides. However, Bt breaks down in the sun's ultraviolet rays, and GE crops with the Bt trait have been shown to accumulate Bt in the soil beyond the sun's rays.

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