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Substance abuse is a diverse and widespread societal problem. Experimentation often begins as early as the sixth grade (Simons-Morton, Haynie, Crump, Eitel, & Saylor, 2001) and can extend even into old age (Patterson & Jeste, 1999). Given the extensive time period during which substance abuse can develop, it is important that this disorder be understood in the appropriate developmental context. Although the pattern may change throughout the course of a lifetime, it is clear that substance abuse can lead to disastrous consequences at any age.

The chief social, biological, and developmental factors that can affect the substance use disorders are presented below, along with a description of these disorders, as defined by the American Psychiatric Association. Each of these factors is presented as part of the developmental period to which it is most pertinent; however, some factors (e.g., comorbidity, heredity) may not be exclusive to a particular period.

Substance Use Disorders

The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) (American Psychiatric Association, 1994) defines substance-related disorders as related to “the taking of a drug of abuse (including alcohol), to the side effects of a medication, and to toxin exposure” (p. 175). Included under this heading are the two substance use disorders, namely, substance dependence and substance abuse.

Substance Dependence

The hallmark of dependence is the continued use of a substance despite the experience of significant psychological and/or physiological symptoms related to intake (American Psychiatric Association, 1994). Prominent features include tolerance, the need to consume increasing amounts of the substance in order to maintain the desired level of intoxication, and withdrawal, the experience of unpleasant physiological symptoms that occurs when intake of the substance declines or ceases entirely. In addition, dependent individuals often experience a disruption in the performance of daily activities, a departure from social relatioships, and unsuccessful attempts to cut down or eliminate their substance use.

Substance Abuse

Substance abuse is characterized by a pervasive pattern of substance use that results in undesirable consequences for the user (American Psychiatric Association, 1994). These consequences often include legal problems, an inability to fulfill responsibilities, and interpersonal problems. Substance abuse is considered a lesser form of the disorder and can be distinguished from dependence by the absence of significant physical or physiological problems related to use.

Substance Use in Adolescence

Most studies of substance use, particularly those pertaining to alcohol, are conducted with adolescents or college-aged young adults. This is most likely the result of a combination of factors, including the relative ease of accessibility (e.g., through schools and universities) and the pervasiveness of use in this population. Despite the fact that research on substance use with adolescents or young adults is common practice, relatively few of these studies have focused on the developmental issues unique to this group and how they may affect the course of a substance use disorder. The following sections describe some of these issues and their relationship to the study of substance use in adolescence and young adulthood.

Normal Experimentation

Alcohol and drug use among adolescents is a devastating problem in our society. However, it is important to distinguish between age-appropriate experimentation and problem use. Not all adolescents who experiment with alcohol or drugs will develop a crippling dependence. In one study of adolescent drug use and psychological health, 68% of a general sample had tried marijuana, 37% had tried cocaine, 25% had tried hallucinogens, and approximately 10% had tried amphetamines, barbiturates, tranquilizers, or inhalants (Shedler & Block, 1990). Although these statistics are disturbing, it is highly unlikely that all of these adolescents will experience problems with substance use later in life. In fact, Shedler and Block found a curvilinear relationship between the frequency of drug use and psychological health; that is, experimenters were psychologically healthier than both abstainers and frequent users. When compared with the experimenters, frequent users were “alienated, deficient in impulse control, and manifestly distressed” and abstainers were “anxious, emotionally constricted, and lacking in social skills” (Shedler & Block, 1990, p. 624). These results suggest that some degree of drug experimentation is a typical part of adolescent development and does not necessarily lead to problematic use.

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