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First classified in the 1970s, anorexia nervosa (AN) is a commonly recognized eating disorder characterized by both restrictive eating behaviors designed to produce or maintain a very low body weight and intense preoccupation with weight and shape (see Table 1 for complete diagnostic criteria). There are two subtypes of AN: restricting type (those who do not binge and purge) and binge-eating/purging type (those who regularly binge and purge). Binge-eating/purging AN is differentiated from another eating disorder involving binging and purging, bulimia nervosa, by the low body weight and amenorrhea of those with AN. One cannot be dually diagnosed with multiple eating disorders; the AN diagnosis should prevail if diagnostic criteria are met. However, shifting from one type of eating disorder to another (e.g., bulimia nervosa) is not uncommon.

Etiology

Anorexia often develops in early to midadolescence following a successful weight loss attempt that subsequently spirals out of control. It is rare, but possible, for prepubertal children to develop the disorder as well. Individuals diagnosed with AN are most often female; only 5% to 10% are male. Estimates of prevalence in the population of those meeting full diagnostic criteria range from 0.28% to 1.0%, although the numbers may be greater in special high-risk populations, such as ballet dancers or those in appearance-conscious professions. Historically, eating disorders were considered to affect primarily middleto upper-class Caucasian women in Western cultures. Recent research suggests that a trend of body image dissatisfaction is rising among many ethnic minority groups in the United States, particularly Hispanics and Asian Americans (e.g., Cachelin, Veisel, Barzegarnazari, & Striegel-Moore, 2000). Cross-cultural rates of eating disorders appear to be increasing as well. This increasing diversity of people with eating disorders introduces additional challenges for research and treatment.

Table 1. Diagnostic Criteria for AN
Refusal to maintain body weight at or above a minimally normal weight for age and height (e.g., weight loss leading to maintenance of body weight less than 85% of that expected, or failure to make expected weight gain during period of growth, leading to body weight less than 85% of that expected).
Intense fear of gaining weight or becoming fat, even though underweight.
Disturbance in the way in which one's body weight or shape is experienced, undue influence of body weight or shape on selfevaluation, or denial of the seriousness of the current low body weight.
In postmenarcheal females, amenorrhea (i.e., the absence of at least three consecutive menstrual cycles).
Specific type:
Restricting type: During the current episode of anorexia nervosa, the person has not regularly engaged in binge-eating or purging behavior (i.e., self-induced vomiting or the misuse of laxatives, diuretics, or enemas).
Binge-eating/purging type: During the current episode of anorexia nervosa, the person has regularly engaged in binge-eating or purging behavior (i.e., self-induced vomiting or the misuse of laxatives, diuretics, or enemas).

There are multiple possible contributors to the development of AN. Genetics appears to play an important role. Twin studies show that the concordance rate of AN is 55% among monozygotic twins and 5% in dizygotic twins (Treasure & Holland, 1989). Other research indicates that a genetic predisposition for leanness or particular personality traits (e.g., perfectionist or obsessive personality) may also contribute to the development of AN. Environmental factors, such as societal emphasis on thinness and appearance or familial attitudes toward weight are also likely to play a role. Further research is needed in this area to aid in efforts to prevent eating disorders.

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