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Duke Longitudinal Studies
The Duke Longitudinal Studies of Aging, initiated in 1955, consist of two separate studies. The first longitudinal study began in 1955 with 271 persons 60 to 90 years of age. The participants were not a probability sample but rather were selected from a pool of volunteers who lived in Durham, North Carolina. Each panelist came to the Duke Medical Center for a 2-day series of medical, psychiatric, psychological, and social examinations. The examinations were repeated periodically until 1996.
The second longitudinal study, also known as the Adaptation Study, began in 1968 with 502 persons 46 to 70 years of age. These panelists were a probability sample of members of the local health insurance association stratified by age and sex. The study was designed so that at the end of 5 years, there would remain approximately 40 persons in each of 10 5-year age–sex cohorts. This design makes possible various kinds of cross-sequential analyses to separate the effects of age, period, and cohort.
Purposes
The studies focused on “normal aging” in two senses: healthy aging and typical aging. Those persons studied were relatively healthy in that most were ambulatory community residents who were willing and able to come to the Duke Medical Center for tests and examination. The studies focused on more common or typical patterns and problems of aging rather than on abnormalities. The goal was to help distinguish between normal processes of aging and those that may accompany aging because of accident, stress, maladjustment, or disuse.
A second purpose was to use the longitudinal method of repeated observations over time—the best way to measure changes accurately—and the effect of one kind of change on another kind of change. The third purpose was to do as much interdisciplinary analysis as possible.
Themes
The five volumes reporting the results of these studies contain more than 100 specific findings. However, four general themes tie together the findings from several substantive areas.
- Declining health and physical function. This is the typical pattern of normal aging in most areas.
- Exceptions to physical decline. Substantial minorities show no decline and may even have improvement in sexual activity, cardiovascular function, hypertension, depression, health ratings, and so on.
- Little or no decline in social and psychological function. Intelligence, as measured by the usual tests, shows much less decline over time than cross-sectional studies imply. Older adults also maintain their social contacts and do not disengage from their social networks.
- Wide variations in aging patterns. Individual variation tends to persist or increase with aging.
In summary, the Duke Longitudinal Studies found that normal aging includes many patterns of change, including stability and even improvement.
Further Readings and References
- Aging and the Brain
- Alzheimer's Disease
- Apolipoprotein E
- Consortium to Establish a Registry for Alzheimer's Disease
- Creutzfeldt–Jakob Disease
- Delirium and Confusional States
- Imaging of the Brain
- Lewy Body Dementia
- Mental Status Assessment
- Mild Cognitive Impairment
- Neurobiology of Aging
- Neurological Disorders
- Pick's Disease
- Stroke
- Syncope
- Vascular Dementia
- Vascular Depression
- Diseases and Medical Conditions
- Accelerated Aging Syndromes
- Anemia
- Aneurysms
- Arrhythmias
- Arthritis and Other Rheumatic Diseases
- Calcium Disorders of Aging
- Cancer
- Cancer Prevention and Screening
- Cancer, Common Types of
- Cataracts
- Cellulitis
- Congestive Heart Failure
- Diabetes
- Ear Diseases
- Eye Diseases
- Foot Problems
- Fractures in Older Adults
- Gastrointestinal Aging
- HIV and AIDS
- Hypertension
- Iatrogenic Disease
- Immune Function
- Incontinence
- Infections, Bladder and Kidney
- Infectious Diseases
- Kidney Aging and Diseases
- Men's Health
- Menopause and Hormone Therapy
- Metabolic Syndrome
- Musculoskeletal Aging: Inflammation
- Musculoskeletal Aging: Osteoarthritis
- Oral Health
- Osteoporosis
- Pneumonia and Tuberculosis
- Pressure Ulcers
- Sarcopenia
- Shingles
- Skin Neoplasms, Benign and Malignant
- Spinal Stenosis
- Systemic Infections
- Temperature Regulation
- Thyroid Disease
- Valvular Heart Disease
- Venous Stasis Ulcers
- Wound Healing
- Drug-Related Issues
- Function and Syndromes
- Mental Health and Psychology
- Agitation
- Alcohol Use and Abuse
- Anxiety Disorders
- Behavioral Disorders in Dementia
- Bereavement and Grief
- Control
- Delirium and Confusional States
- Depression and Other Mood Disorders
- Emotions and Emotional Stability
- Expectations Regarding Aging
- Life Course Perspective on Adult Development
- Loneliness
- Memory
- Mental Status Assessment
- Mild Cognitive Impairment
- Motivation
- Personality Disorders
- Positive Attitudes and Health
- Posttraumatic Stress Disorder
- Pseudodementia
- Psychiatric Rating Scales
- Psychosocial Theories
- Schizophrenia, Paranoia, and Delusional Disorders
- Selective Optimization With Compensation
- Self-Care
- Self-Efficacy
- Self-Rated Health
- Stress
- Subjective Well-Being
- Successful Aging
- Suicide and the Elderly
- Vascular Depression
- Nutritional Issues
- Physical Status
- Allostatic Load and Homeostasis
- Biological Theories of Aging
- Biomarkers of Aging
- Body Composition
- Body Mass Index
- Cardiovascular System
- Compression of Morbidity
- Fluid and Electrolytes
- Hearing
- Men's Health
- Multiple Morbidity and Comorbidity
- Normal Physical Aging
- Perioperative Issues
- Pulmonary Aging
- Skin Changes
- Skin Neoplasms, Benign and Malignant
- Sleep
- Surgery
- Temperature Regulation
- Therapeutic Failure
- Vision and Low Vision
- Women's Health
- Prevention
- Sociodemographic and Cultural Factors
- Active Life Expectancy
- Africa
- African Americans
- Age–Period–Cohort Distinctions
- Asia
- Asian and Pacific Islander Americans
- Australia and New Zealand
- Canada
- Caregiving
- Centenarians
- Compression of Morbidity
- Critical Perspectives in Gerontology
- Demography of Aging
- Disasters and Terrorism
- Disclosure
- Early Adversity and Late-Life Health
- Economics of Aging
- Education and Health
- Elder Abuse and Neglect
- Environmental Health
- Epidemiology of Aging
- Ethical Issues and Aging
- Ethnicity and Race
- Europe
- Expectations Regarding Aging
- Global Aging
- Health Communication
- Hispanics
- Homelessness and Health in the United States
- Latin America and the Caribbean
- Life Course Perspective on Adult Development
- Living Arrangements
- Loneliness
- Longevity
- Marital Status
- Mexico
- Midlife
- Migration
- Multiple Morbidity and Comorbidity
- Native Americans and Alaska Natives
- Negative Interaction and Health
- Oldest Old
- Quality of Life
- Rural Health and Aging Versus Urban Health and Aging
- Social Networks and Social Support
- Socioeconomic Status
- Stress
- Successful Aging
- Work, Health, and Retirement
- Studies of Aging
- Aging in Manitoba Longitudinal Study
- Cardiovascular Health Study
- Clinical Trials
- Critical Perspectives in Gerontology
- Duke Longitudinal Studies
- Epidemiology of Aging
- Established Populations for Epidemiologic Studies of the Elderly
- Government Health Surveys
- Health and Retirement Study
- Hispanic Established Population for Epidemiologic Studies of the Elderly
- Honolulu–Asia Aging Study, Honolulu Heart Program
- Longitudinal Research
- Longitudinal Study of Aging
- MacArthur Study of Successful Aging
- National Health Interview Survey
- National Long Term Care Survey
- Normative Aging Study
- Qualitative Research on Aging
- Twin Studies
- Systems of Care
- Advance Directives
- Advocacy Organizations
- Aging Network
- Assisted Living
- Caregiving
- Complementary and Alternative Medicine
- Continuum of Care
- Death, Dying, and Hospice Care
- Elder Abuse and Neglect
- Ethical Issues and Aging
- Geriatric Profession
- Geriatric Team Care
- Gerontological Nursing
- Health and Public Policy
- Health Care System for Older Adults
- Home Care
- Institutional Care
- Legal Issues
- Long-Term Care
- Long-Term Care Insurance
- Managed Care
- Medicaid
- Medicare
- Minimum Data Set
- National Institute on Aging
- Nursing Roles in Health Care and Long-Term Care
- Outcome and Assessment Information Set (OASIS)
- Palliative Care and the End of Life
- Patient Safety
- Pets in Health Care Settings
- Rehabilitation Therapies
- Self-Care
- Social Work Roles in Health and Long-Term Care
- Telemedicine
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