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Chapter 3: Future Directions: The Role of Pharmacogenomics
It is inevitable that genetic information will become both increasingly available and of increasing importance in the health system. As a consequence of these developments, genetic information that is relevant to drug use and addiction will also become available. That information has the potential to transform our understanding of drug use and drug-related problems, both at a general level and at the level of the individual user and treatments.
Genotype can influence the concentration of the drug reaching its site of action and the activity of the drug. Concentration at the site is determined by the action of enzymes impacting on drug ...