With contributions from leading international academics across the biological sciences, this handbook takes a critical look at the key contemporary issues and debates in the field. The 31 chapters are divided into four parts: Part I Determination of Substance Misuse Part II PK and PD in Relation to Patterns of Use Part III Detection and Treatment of Drug and Alcohol Use Part IV Controversies and New Approaches This Handbook is an excellent reference text for the growing number of academics, students, scientists and practitioners in the drug and alcohol studies community, and will be a vital resource to the allied professions involved in work-place drug testing, clinical toxicology, and forensic science.

Chapter 16: Polysubstance Use

Polysubstance Use

Polysubstance Use
Jason P. ConnorGerald F. X. FeeneyAdrian B. KellyJohn B. Saunders

DEFINITION, PREVALENCE AND TRENDS

Polysubstance use is the consumption of more than one drug at the same or different times, typically for recreational purposes and pleasurable effects. It has been described as a phenomenon of the modern world, in which an ever increasing selection of chemical substances is available for consumption. There is a danger that the widespread use of the term polysubstance use conceals what for some people are highly functional combinations of drugs, what for some are highly risky combinations and in others seems so indiscriminate as to defy pharmacological understanding. It is the premise of this chapter that polysubstance use is a highly important topic and one that requires scientific ...

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