High rates of personality disorder are consistently identified among populations diagnosed with substance use disorders (SUDs). Rates of co-occurrence with SUD are particularly high for personality disorders within the dramatic-erratic (Cluster B) subcategory of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) Axis II. Of the personality disorders, antisocial personality disorder (ASPD) exhibits the highest rates of cooccurrence with SUD. Large-scale epidemiological studies have identified rates of co-occurrence between ASPD and SUD that dramatically exceed rates observed between other forms of psychopathology, and although these rates vary considerably across populations and studies, the prevalence of ASPD among SUD populations is many times higher than the 2% to 3% observed in the general population. Indeed, according to some estimates, individuals with ...

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