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Imaging Aging: Present and Future
Imaging aging: Present and future

Traditionally, cognitive aging research has been based on behavioral measures of cognitive performance such as response time and accuracy. Data have indicated that age-related decline occurs in multiple cognitive functions (e.g., speed of processing, attention, episodic memory), whereas others remain relatively well preserved (e.g., semantic knowledge). Given that cognitive processes depend on brain anatomy and physiology, previously observed behavioral changes in aging are likely intimately linked to changes in the integrity of cerebral architecture and function. As novel imaging techniques have been developed, application to age-related issues typically occurs shortly thereafter. For instance, over 60 years ago, cerebral blood flow in humans was assessed by having research participants inhale nitrous oxide and measuring the difference in ...

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