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Recovery of Vision following Blindness

In 1688, William Molyneux sent a letter to John Locke in which he asked whether a man born blind, who had learned to distinguish a globe and a cube by touch, would be able to distinguish them by vision alone, if sight were ever restored. It was not until almost 30 years after the posing of Molyneax's problem that the surgeon William Cheselden reported that a patient whose sight had been restored after years of blindness did indeed have acute difficulties interpreting the visual world. Trying to understand the extent and cause of these difficulties played an important role in the development of 18th-century philosophy as empiricist philosophers, such as Etienne Bonnot de Condillac, Denis Diderot, and Thomas Reid, refined their opinions about the relationship between perceptual concepts and sensory experience, and began to differentiate internal psychological events, such as sensations, perceptions, and cognitive constructs. This entry discusses cases of sight recovery and restored visual abilities.

Cases of Sight Recovery

Although the first recorded case of sight recovery was in 1020 A.D., only sporadic cases have been studied over the last 3 centuries. More notable cases include SB (1963), HS (1971), HB (1974), and more recently Virgil (1995), MM (2003), and SRD (2006). It should be noted that none of the cases of sight recovery currently recorded in the literature are considered “pure” sight recovery as defined by no light perception from birth to adulthood. Because all patients had intact retinas, they necessarily had some light perception, and in many cases rudimentary form vision, preoperatively. In most cases, sight recovery has been due to cataract removal in adulthood. Because of the current emphasis on early diagnosis and treatment of visual disorders, sight recovery in adulthood now generally occurs as a result of misdiagnosis, a lack of medical facilities, or associated ophthalmological complications that require treatment before successful cataract removal.

As well as differing in the amount of preoperative vision, most sight recovery patients were only studied some months or years after sight recovery had occurred. Nonetheless, despite these important differences across patients, some consensus has gradually emerged about the restored visual abilities of those who have lost their sight early in childhood.

Restored Visual Abilities

Most sight-recovery patients can name colors easily and can distinguish fine differences in hue. Motion processing also appears to be relatively spared. It was said of SB that the only visual objects he appreciated were those that were moving, such as birds. Similarly, for HB, it was reported that she could see the pigeons as they alighted in Trafalgar Square, but said that they appeared to vanish as they came to rest. MM had no difficulty on motion tasks that included identifying the direction of motion of bars, segregating textured fields based on motion, and using motion cues to compute the three-dimensional (3-D) shape of a rotating cube (see Figure 1a). MM was also sensitive to biological motion, recognizing a biological motion point-light “Johansson” figure, and was even able to resolve the fine cues that differentiate male and female gaits.

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