According to the U.S. Global Health Initiative, the term global health initiative (GHI) means working to institute an integrated, coordinated, and result-driven approach to global health. The term represents a series of global humanitarian efforts geared toward generating and disbursing funds for the prevention and treatment of infectious diseases, including human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), malaria, and tuberculosis. GHIs are also focused on immunization provision and establishing and strengthening health care delivery systems in developing and least developed countries (LDCs). They are an integral effort within the framework of global health diplomacy and have fostered globalization and provided care for much of the world’s ailing population.