Discrimination is defined as the unjust mistreatment of a person or group of persons on the basis of perceived differences such as race, gender, sex, class, ability, and/or sexual orientation. This entry addresses the social, political, and legal domains of discrimination that trans people face in the United States. It also addresses the ways in which social, political, and legal discrimination are entangled. Further complicating the matter is the fact that trans people belong to many other relational classifications such as race. Racism and transphobia can often overlap. As a consequence, trans Black women and trans youth of color are disproportionately affected by discrimination. Thus, discrimination against trans people takes many forms, from the highest levels of representative government to everyday encounters in the public ...