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The two hallmarks of pluripotent stem cells are their ability to differentiate into all cell types within the embryo except the germ cells, sperm or ova, and their capability for unlimited proliferation. Selective markers have been utilized to identify pluripotent stem cells both in tissue isolates and within the tissues proper. The majority of these markers are either modified proteins or glycolipids that occur on the cell surface and help to identify the activity and character of the cell on which they reside. Examples of such markers include CD34, CD133, LGR5, Nestin, SSEA-3, SSEA-4, TRA-1-60, and TRA-1-81.

CD 34

CD34 (cluster of differentiation 34) is a transmembrane protein marker employed in differentiating hematopoietic stem cells (HSCs) and progenitor cells from other cell lines in procedures involving transplantation ...

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