Stem Cell Genetic Modification Study Method

The importance and applications of stem cells in the biomedical field have gained tremendous attention because of their potential role in the treatment of disease. However, the ultimate goal of reaching the clinic requires extensive investigations on the molecular, cellular, and genetic activities of stem cells. One of the most informative and essential methods of understanding the dynamics of stem cells is through the induction of genetic modification in these pluripotent stem cells. By removing or mutating specific genes in stem cells, it is possible to determine the actual role of particular genes or gene networks in the properties of self-renewal and differentiation of pluripotent entities.

Introducing Mutations Into Stem Cells

During the past decades, various approaches to the genetic modification of embryos have been conducted to ...

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