Nuclear Transfer, Altered

Approximately 15 years ago, the first report on the isolation of human embryonic stem cells was released, stirring excitement in the scientific community and major ethical concerns in the rest of society. The controversial benefits of the use of human embryonic stem cells then resulted in the freezing of federal research funds in the United States, thus allowing the rest of the international scientific community to move forward in this research field. By 2005, the bioethics committee of the U.S. President’s Council issued a proposal on generating pluripotent stem cells that did not involve the destruction of embryos. The technique of altered nuclear transfer (ANT) was then presented, which prompted the interest of various laboratories to embark on extensive studies to determine its mechanism and ...

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