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Ernest McCulloch was a physician and University Professor Emeritus at the University of Toronto until his death in 2011. He is widely regarded as one of the founders of stem cell research, along with his major collaborator James Till. The implications of this work led to key discoveries in the drive to develop effective bone marrow transplantation techniques and in stem cell research.

McCulloch was born in Toronto, Ontario, Canada, in 1926 and received a secondary education at Upper Canada College, a private high school. He then went directly to medical school at the University of Toronto, as undergraduate degrees were not required at the time for entry into medical school. He received his medical degree there at age 22. His research career began at ...

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