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Bone: Existing or Potential Regenerative Medicine Strategies

Bone is a supporting tough tissue that provides structure to the body and aids movement by cooperating with the muscles. We have over 200 bones in our bodies, forming the skeletal structure and weighing approximately 2 kilograms (kg). Bone is a unique tissue that constantly undergoes remodeling through the period of adult life. Bone defects result from tumor resection, congenital malformations, trauma, fractures, periodontitis, and diseases such as arthritis and osteoporosis. Clinically, healing of fractures is a natural phenomenon in which bone regeneration occurs as part of the healing process. Bone is the only tissue where there is no scar tissue formation in the healing process, and the constant remodeling of the bone is one of the factors that facilitate this regeneration.

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