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Bone: Current Research on Isolation or Production of Therapeutic Cells

Bone is one of the tissue types that undergo constant remodeling during the lifetime of the organism. By virtue of this property, bone is mostly able to regenerate. Healing of fractures is one example of bone regenerating, but regeneration potential is limited, and some autoimmune diseases are associated with erosion of the bone. Traumatic injuries also result in non-union fractures—fractures that do not heal, as there is no union. A fix for such situations is to create a micro-environment in which bone regeneration is more efficient. Bone morphogenic protein or BMP is one of the factors that promote efficient regeneration of the bone. This requires topical application to the site of injury, which then promotes efficient regeneration. Disadvantages of this method include that it does ...

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