SAGE Reference - The SAGE Encyclopedia of Lifespan Human Development

Entry
Reader's guide
Entries A-Z
Subject index

Androgen Insensitivity Syndrome

By: Bruce Gottlieb
In: The SAGE Encyclopedia of Lifespan Human Development
Edited by: Marc H. Bornstein
Subject:Lifespan Development, Lifespan & Developmental Psychology (general)
Keywords:chromosomes; estrogen replacement therapy; genetic testing; mutation; puberty; syndromes; testes

Androgen insensitivity syndrome (AIS) occurs when a person who carries the genetic code for male (one X chromosome and one Y chromosome) appears to be female. This entry covers the following: a brief description of the clinical features of the syndrome, diagnosing and testing, management and treatment, detecting carriers, genetic counseling to identify carriers, gender assignment issues, AIS in adulthood, and self-help groups and other resources.

Clinical Features

The clinical manifestations of AIS can be broadly divided into three groups, assumed to be the result of the degree of androgen insensitivity—that is, responsiveness to male hormones. Complete androgen insensitivity syndrome (CAIS) is when the individual with XY chromosome combination appears with typical female external genitalia. Partial androgen insensitivity syndrome (PAIS) involves predominantly female, predominantly male, or ambiguous ...

Tools
Tools icon close
- Add to list Added to list Added
- Download PDFopens in new window
- Cite
  
  Cite icon close
  
  Format APA
  
  Gottlieb, B. (2018). Androgen insensitivity syndrome. In M. Bornstein (Ed.), The SAGE encyclopedia of lifespan human development (pp. 119-121). SAGE Publications, Inc., https://www.doi.org/10.4135/9781506307633.n49
  
  Gottlieb, Bruce. "Androgen Insensitivity Syndrome." In The SAGE Encyclopedia of Lifespan Human Development, edited by Bornstein, Marc H., 119-21. Thousand Oaks,, CA: SAGE Publications, Inc., 2018. http://dx.doi.org/10.4135/9781506307633.n49.
  
  Gottlieb, B. 2018. Androgen Insensitivity Syndrome. In: Marc H. Bornstein Editor, 2018. The SAGE Encyclopedia of Lifespan Human Development, Thousand Oaks,, CA: SAGE Publications, Inc. pp. 119-121 Available at: <http://www.doi.org/10.4135/9781506307633.n49> [Accessed 21 Jun 2021].
  
  Gottlieb, Bruce. "Androgen Insensitivity Syndrome." The SAGE Encyclopedia of Lifespan Human Development. Edited by Marc H. Bornstein. Thousand Oaks,: SAGE Publications, Inc., 2018, pp. 119-21. SAGE Knowledge. 21 Jun 2021, doi: http://www.doi.org/10.4135/9781506307633.n49.
  copy to clipboard
  or
  
  Export to your reference manager Endnote
  
  Export
  
  Cancel
- Share
  
  Share icon close
  
  Share via
  
  Email
  
  Please log in from an authenticated institution or log into your member profile to access the email feature.
  
  Sign in/register
- Text size
  
  Text Size close
  
  small
  
  Medium
  
  Large
  
  Cancel
- Get link
  
  Get link icon close
  
  Link to this page directly with a permalink: https://sk.sagepub.com/Reference/the-sage-encyclopedia-of-lifespan-human-development/i3322.xml
  
  Copy to clipboard
  
  Cancel
On this page
On this page icon close
On this page

Data resources

Document resources

Video resources

Sign in to access this content

Get a 30 day FREE TRIAL

Watch videos from a variety of sources bringing classroom topics to life
Read modern, diverse business cases
Explore hundreds of books and reference titles

Androgen Insensitivity Syndrome

Clinical Features

Sign in to access this content

Get a 30 day FREE TRIAL

Read next

More like this

SAGE Recommends