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Laryngopharyngeal Reflux (LPR)

Laryngopharyngeal reflux (LPR) is the retrograde flow of gastric contents into the upper aerodigestive tract caused by a dysfunction in the upper esophageal sphincter. LPR affects up to 50% of individuals with voice disorders and has recently been reported as one of the most frequently encountered chronic inflammatory conditions of the larynx. This entry details a review of the characteristics and clinical manifestations, diagnosis and treatment, and the impact of LPR on voice and swallowing.

Clinical Manifestations

The most common indicator of LPR is reflux laryngitis, inflammation of the larynx. At times, granulomas can be visualized in the cartilages of the larynx as a result of persistent LPR. Other signs and symptoms include dysphonia, vocal fatigue, excessive throat clearing, cough, globus sensation, and dysphagia. Chronic, untreated LPR ...

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