Assent refers to the agreement of an individual, typically a minor, to participate in research or treatment. Assent is similar to consent, except that assent is reserved for individuals lacking the capacity to provide consent due to impairments or limitations in reasoning or judgment. If a person is deemed unable to make informed, autonomous decisions based on legal, medical, or ethical standards, consent must be obtained from a guardian or a surrogate. When appropriate, the individual’s assent is sought secondary to the consent of someone with legal authority as an indication that the individual agrees to undergo treatment or participate in research. Although assent is not a legally binding form of authorization, refusal to assent can be ethically binding, particularly when involving possible research ...

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