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Major or Mild Neurocognitive Disorder due to Traumatic Brain Injury

The U.S. Department of Veterans Affairs/Department of Defense’s Clinical Practice Guidelines defines traumatic brain injury (TBI) as traumatically induced structural injury and/or physiological disruption of brain function as a result of an external force that is indicated by new onset or worsening of at least one of the following clinical signs immediately following the event:

  • Any period of loss of or a decreased level of consciousness
  • Any loss of memory for events immediately before or after the injury (posttraumatic amnesia)
  • Any alteration in mental state at the time of the injury (e.g., confusion, disorientation, slowed thinking)
  • Neurological deficits (e.g., weakness, loss of balance, change in vision, praxis, paresis/plegia [weakness/paralysis], sensory loss, aphasia [loss of speech]) that may or may not be transient
  • Intracranial lesion (as seen from structural brain imaging, ...
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