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Intent-to-Treat
The intent-to-treat principle, also known as the intention-to-treat (ITT) principle, refers to a strategy that analyzes all patients with follow-up information according to the intervention group that they are assigned to by the study’s randomization procedure regardless of their eligibility, adherence, or withdrawal status. The ITT principle encompasses both the group being analyzed and how the analysis itself is conducted. Randomized prospective trials designed to compare two or more interventions are most effective if the ITT principle is used.
The Design of Randomized Prospective Studies
Many medical and behavioral studies seek to accurately compare two or more interventions in a cohort where the use of such interventions is appropriate. Intervention refers to a therapeutic or treatment strategy administered to individuals in the study. In psychiatry or behavioral ...
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