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Hallucinogen withdrawal is occasionally mentioned by those attempting to sell “detoxification” strategies or other interventions to an unwitting public, but because hallucinogens in general do not induce physiological dependence, there is no classic withdrawal syndrome. Our society broadly condemns the use of hallucinogens and criminalizes their possession or use (except in limited sanctioned religious and Native traditional contexts). This makes it difficult to learn about their actual nature; research has progressed slowly, and public awareness has lagged behind propaganda.

Classical hallucinogens, such as LSD (lysergic acid diethylamide) or psilocin (psilocybin found in Psilocybe sp. mushrooms is metabolized into its psychoactive congener psilocin), do not cause any direct symptoms or syndromes of withdrawal. Many repeated behaviors or chronic use of various other drugs can cause distress ...

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