Depressive disorders in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), include major depressive disorder (MDD), persistent depressive disorder (PDD; which combines chronic MDD and dysthymic disorder from the DSM-IV-TR [Text Revision]), disruptive mood dysregulation disorder (DMDD), premenstrual dysphoric disorder (PMDD), substance/medication-induced depressive disorder, other specified depressive disorder, and unspecified depressive disorder. In the United States, 20.8% of individuals will meet diagnostic criteria for at least one of these depressive disorders in their lifetime; this is referred to as lifetime prevalence and is distinct from the proportion of a population of people who meet diagnostic criteria at a particular point in time (point prevalence) or during a specified period of time (period prevalence). The rate of new (or newly diagnosed) cases of ...