The Center for Substance Abuse Prevention (CS AP) is the lead federal agency responsible for improving the quality and accessibility of substance abuse prevention services. The CSAP replaced the Office for Substance Abuse Prevention (OSAP), which was established by the Anti-Drug Abuse Act of 1988 as part of the Alcohol, Drug Abuse, and Mental Health Administration (ADAMHA) under the Department of Health and Human Services. When the Substance Abuse and Mental Health Services Administration (SAMHSA) replaced ADAMHA, through reorganization in 1992, OSAP became the CSAP.

The general mission of the CSAP is to provide national leadership for policies, programs, and services to prevent the onset of illicit drug use and underage alcohol and tobacco use and to reduce the negative consequences of substance use. It ...

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