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Nuclear Transfer, Somatic

SOMATIC CELL NUCLEAR TRANSFER (SCNT) is a process that was developed with the intent of producing immunologically compatible pluripo—tent embryonic cells that could be used for treating human diseases. Thus, SCNT was also termed therapeutic cloning. These pluripotent embryonic cells would be able to develop into any type of cell in the human body, and in addition, the technique used for these cells would address two important medical issues: immune system rejection and finding a genetically matching human donor.

The technique of SCNT involves the removal of the nucleus of an unfertilized egg cell (oocyte) and replacing it with the nucleus of a somatic cell. Somatic cells are nongermline cells that make up most cells in the body (e.g., cells found in bone, connective tissue, blood, ...

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