Epstein-Barr Virus, Infectious Mononucleosis, and Splenomegaly

Infectious mononucleosis (IM) accounts for considerable morbidity and even mortality in physically active young adults. In the United States, IM has a peak incidence between 15 and 21 years of age, and 1% to 3% of college students may become infected yearly. There is no evidence that IM is more prevalent or less prevalent in athletes.


IM is caused by the Epstein-Barr virus (EBV), which is a member of the herpes virus family. It is excreted in the saliva and infects only humans. IM is transmitted by close contact ...

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