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Group-Sequential Designs in Clinical Trials
If the main interest of a clinical trial is to determine whether a new treatment results in a better outcome than the existing treatment, investigators often would like to obtain the result as soon as possible. One of the reasons for ...
- Descriptive Statistics
- Distributions
- Graphical Displays of Data
- Hypothesis Testing
- Alternative Hypotheses
- Beta
- Critical Value
- Decision Rule
- Hypothesis
- Nondirectional Hypotheses
- Nonsignificance
- Null Hypothesis
- One-Tailed Test
- p Value
- Power
- Power Analysis
- Significance Level, Concept of
- Significance Level, Interpretation and Construction
- Significance, Statistical
- Two-Tailed Test
- Type I Error
- Type II Error
- Type III Error
- Important Publications
- “Coefficient Alpha and the Internal Structure of Tests”
- “Convergent and Discriminant Validation by the Multitrait-Multimethod Matrix”
- “Meta-Analysis of Psychotherapy Outcome Studies”
- “On the Theory of Scales of Measurement”
- “Probable Error of a Mean, The”
- “Psychometric Experiments”
- “Sequential Tests of Statistical Hypotheses”
- “Technique for the Measurement of Attitudes, A”
- “Validity”
- Aptitudes and Instructional Methods
- Doctrine of Chances, The
- Logic of Scientific Discovery, The
- Nonparametric Statistics for the Behavioral Sciences
- Probabilistic Models for Some Intelligence and Attainment Tests
- Statistical Power Analysis for the Behavioral Sciences
- Teoria Statistica Delle Classi e Calcolo Delle Probabilità
- Inferential Statistics
- Association, Measures of
- Coefficient of Concordance
- Coefficient of Variation
- Coefficients of Correlation, Alienation, and Determination
- Confidence Intervals
- Margin of Error
- Nonparametric Statistics
- Odds Ratio
- Parameters
- Parametric Statistics
- Partial Correlation
- Pearson Product-Moment Correlation Coefficient
- Polychoric Correlation Coefficient
- Q-Statistic
- R2
- Randomization Tests
- Regression Coefficient
- Semipartial Correlation Coefficient
- Spearman Rank Order Correlation
- Standard Error of Estimate
- Standard Error of the Mean
- Student's t Test
- Unbiased Estimator
- Weights
- Item Response Theory
- Mathematical Concepts
- Measurement Concepts
- Organizations
- Publishing
- Qualitative Research
- Reliability of Scores
- Research Design Concepts
- Aptitude-Treatment Interaction
- Cause and Effect
- Concomitant Variable
- Confounding
- Control Group
- Interaction
- Internet-Based Research Method
- Intervention
- Matching
- Natural Experiments
- Network Analysis
- Placebo
- Replication
- Research
- Research Design Principles
- Treatment(s)
- Triangulation
- Unit of Analysis
- Yoked Control Procedure
- Research Designs
- A Priori Monte Carlo Simulation
- Action Research
- Adaptive Designs in Clinical Trials
- Applied Research
- Behavior Analysis Design
- Block Design
- Case-Only Design
- Causal-Comparative Design
- Cohort Design
- Completely Randomized Design
- Crossover Design
- Cross-Sectional Design
- Double-Blind Procedure
- Ex Post Facto Study
- Experimental Design
- Factorial Design
- Field Study
- Group-Sequential Designs in Clinical Trials
- Laboratory Experiments
- Latin Square Design
- Longitudinal Design
- Meta-Analysis
- Mixed Methods Design
- Mixed Model Design
- Monte Carlo Simulation
- Nested Factor Design
- Nonexperimental Design
- Observational Research
- Panel Design
- Partially Randomized Preference Trial Design
- Pilot Study
- Pragmatic Study
- Pre-Experimental Designs
- Pretest-Posttest Design
- Prospective Study
- Quantitative Research
- Quasi-Experimental Design
- Randomized Block Design
- Repeated Measures Design
- Response Surface Design
- Retrospective Study
- Sequential Design
- Single-Blind Study
- Single-Subject Design
- Split-Plot Factorial Design
- Thought Experiments
- Time Studies
- Time-Lag Study
- Time-Series Study
- Triple-Blind Study
- True Experimental Design
- Wennberg Design
- Within-Subjects Design
- Zelen's Randomized Consent Design
- Research Ethics
- Research Process
- Clinical Significance
- Clinical Trial
- Cross-Validation
- Data Cleaning
- Delphi Technique
- Evidence-Based Decision Making
- Exploratory Data Analysis
- Follow-Up
- Inference: Deductive and Inductive
- Last Observation Carried Forward
- Planning Research
- Primary Data Source
- Protocol
- Q Methodology
- Research Hypothesis
- Research Question
- Scientific Method
- Secondary Data Source
- Standardization
- Statistical Control
- Type III Error
- Wave
- Research Validity Issues
- Bias
- Critical Thinking
- Ecological Validity
- Experimenter Expectancy Effect
- External Validity
- File Drawer Problem
- Hawthorne Effect
- Heisenberg Effect
- Internal Validity
- John Henry Effect
- Mortality
- Multiple Treatment Interference
- Multivalued Treatment Effects
- Nonclassical Experimenter Effects
- Order Effects
- Placebo Effect
- Pretest Sensitization
- Random Assignment
- Reactive Arrangements
- Regression to the Mean
- Selection
- Sequence Effects
- Threats to Validity
- Validity of Research Conclusions
- Volunteer Bias
- White Noise
- Sampling
- Cluster Sampling
- Convenience Sampling
- Demographics
- Error
- Exclusion Criteria
- Experience Sampling Method
- Nonprobability Sampling
- Population
- Probability Sampling
- Proportional Sampling
- Quota Sampling
- Random Sampling
- Random Selection
- Sample
- Sample Size
- Sample Size Planning
- Sampling
- Sampling and Retention of Underrepresented Groups
- Sampling Error
- Stratified Sampling
- Systematic Sampling
- Scaling
- Software Applications
- Statistical Assumptions
- Statistical Concepts
- Autocorrelation
- Biased Estimator
- Cohen's Kappa
- Collinearity
- Correlation
- Criterion Problem
- Critical Difference
- Data Mining
- Data Snooping
- Degrees of Freedom
- Directional Hypothesis
- Disturbance Terms
- Error Rates
- Expected Value
- Fixed-Effects Models
- Inclusion Criteria
- Influence Statistics
- Influential Data Points
- Intraclass Correlation
- Latent Variable
- Likelihood Ratio Statistic
- Loglinear Models
- Main Effects
- Markov Chains
- Method Variance
- Mixed- and Random-Effects Models
- Models
- Multilevel Modeling
- Odds
- Omega Squared
- Orthogonal Comparisons
- Outlier
- Overfitting
- Pooled Variance
- Precision
- Quality Effects Model
- Random-Effects Models
- Regression Artifacts
- Regression Discontinuity
- Residuals
- Restriction of Range
- Robust
- Root Mean Square Error
- Rosenthal Effect
- Serial Correlation
- Shrinkage
- Simple Main Effects
- Simpson's Paradox
- Sums of Squares
- Statistical Procedures
- Accuracy in Parameter Estimation
- Analysis of Covariance (ANCOVA)
- Analysis of Variance (ANOVA)
- Barycentric Discriminant Analysis
- Bivariate Regression
- Bonferroni Procedure
- Bootstrapping
- Canonical Correlation Analysis
- Categorical Data Analysis
- Confirmatory Factor Analysis
- Contrast Analysis
- Descriptive Discriminant Analysis
- Discriminant Analysis
- Dummy Coding
- Effect Coding
- Estimation
- Exploratory Factor Analysis
- Greenhouse-Geisser Correction
- Hierarchical Linear Modeling
- Holm's Sequential Bonferroni Procedure
- Jackknife
- Latent Growth Modeling
- Least Squares, Methods of
- Logistic Regression
- Mean Comparisons
- Missing Data, Imputation of
- Multiple Regression
- Multivariate Analysis of Variance (MANOVA)
- Pairwise Comparisons
- Path Analysis
- Post Hoc Analysis
- Post Hoc Comparisons
- Principal Components Analysis
- Propensity Score Analysis
- Sequential Analysis
- Stepwise Regression
- Structural Equation Modeling
- Survival Analysis
- Trend Analysis
- Yates's Correction
- Statistical Tests
- Bartlett's Test
- Behrens-Fisher t′ Statistic
- Chi-Square Test
- Duncan's Multiple Range Test
- Dunnett's Test
- F Test
- Fisher's Least Significant Difference Test
- Friedman Test
- Honestly Significant Difference (HSD) Test
- Kolmogorov-Smirnov Test
- Kruskal-Wallis Test
- Mann-Whitney U Test
- Mauchly Test
- McNemar's Test
- Multiple Comparison Tests
- Newman-Keuls Test and Tukey Test
- Omnibus Tests
- Scheffé Test
- Sign Test
- t Test, Independent Samples
- t Test, One Sample
- t Test, Paired Samples
- Tukey's Honestly Significant Difference (HSD)
- Welch's t Test
- Wilcoxon Rank Sum Test
- z Test
- Theories, Laws, and Principles
- Bayes's Theorem
- Central Limit Theorem
- Classical Test Theory
- Correspondence Principle
- Critical Theory
- Falsifiability
- Game Theory
- Gauss-Markov Theorem
- Generalizability Theory
- Grounded Theory
- Item Response Theory
- Occam's Razor
- Paradigm
- Positivism
- Probability, Laws of
- Theory
- Theory of Attitude Measurement
- Weber-Fechner Law
- Types of Variables
- Validity of Scores
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