Athlete's foot, also known as tinea pedis, is a common superficial dermatophyte (fungal) infection of the foot, affecting approximately 15% of the U.S population. Tinea pedis may be characterized as interdigital, moccasin, or vesiculobullous, depending on the affected site and symptoms. Numerous over-the-counter topical antifungal products provide effective treatment and vary by dosage form, frequency, and duration of therapy. While it is important to recognize and treat athlete's foot as soon as symptoms arise, appropriate foot hygiene is key to preventing the spread of infection.