Case-fatality rate (CFR) is a clinical measure that describes a person's likelihood of dying from a disease once he or she is diagnosed with it. It is calculated by dividing the number of deaths from a specified disease during a specified time by the number of individuals who have that disease during that time and multiplying this ratio by 100. It is a measure of disease severity and is often used for prognosis. It can also be used to evaluate the effect of new treatments—with improved treatments, the CFR is expected to decrease. The CFR is not a constant; it can vary between populations and over time depending on the interplay between agent, host, and environment, as well as available treatments and quality of ...

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