• Entry
  • Reader's guide
  • Entries A-Z
  • Subject index

Dose-Response Relationship

  • In: Encyclopedia of Epidemiology
  • Edited by: Sarah Boslaugh
  • Subject:Public Health (general), Public Health Research Methods , Epidemiology & Biostatistics

Dose-response is a term that describes a relationship between an exposure and the risk of an out come. A dose-response relationship is one in which increasing levels of exposure are associated with either increasing or decreasing risk of the outcome. Demonstration of a dose-response relationship is considered strong evidence for a causal relationship between the exposure and the outcome, although the absence of a doseresponse relationship does not eliminate the possibility of a causal relationship.

The increase in the exposure can be in its intensity or its duration. Exposure can be characterized in different ways such as the peak exposure; the duration of exposure at or above a set level; average exposure, which is a time-weighted average of exposure; or cumulative exposure, which is the sum ...

    • Loading...
    locked icon

    Sign in to access this content

    Get a 30 day FREE TRIAL

    • Watch videos from a variety of sources bringing classroom topics to life
    • Read modern, diverse business cases
    • Explore hundreds of books and reference titles