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Rohit Jaibhagwan Lodhi, David Rossolatos & Katherine Jean Aitchison

In: The SAGE Handbook of Drug & Alcohol Studies Volume 2

Chapter 1: Genetics and Genomics in Addiction Research

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Genetics and Genomics in Addiction Research
Genetics and Genomics in Addiction Research
Rohit Jaibhagwan LodhiDavid RossolatosKatherine Jean Aitchison
Introduction

Substance use disorders are complex, multifactorial disorders that are typically characterized by the repeated use of a psychoactive substance that continues despite harmful consequences or varying degrees of impairment in function (American Psychiatric Association, 2013). Internet addiction, gambling disorders and sexual addiction are examples of a broader concept of addictions that is not simply limited to psychoactive substance use. The current approach towards studying genetic influences in such addictions involves much more than looking at the dichotomy of a disorder being present or absent. Agrawal et al. (2012) highlighted the importance of looking at addiction in stages, with early stages being less affected by genetic factors than the ...

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