Previous Chapter Chapter 13: Synthetic Cannabinoids: The Pharmacokinetics and Pharmacodynamics of Spice and Other Synthetic Cannabinoids Next Chapter

Aarti Gupta & Deepak Cyril D'Souza

In: The SAGE Handbook of Drug & Alcohol Studies Volume 2

Chapter 13: Synthetic Cannabinoids: The Pharmacokinetics and Pharmacodynamics of Spice and Other Synthetic Cannabinoids

  • Citations
  • Add to My List
  • Text Size

Synthetic Cannabinoids: The Pharmacokinetics and Pharmacodynamics of Spice and Other Synthetic Cannabinoids
Synthetic Cannabinoids: The Pharmacokinetics and Pharmacodynamics of Spice and Other Synthetic Cannabinoids
Aarti GuptaDeepak Cyril D'Souza
Introduction

Synthetic cannabinoids (SC) have emerged over this past decade as drugs of abuse globally. While these products are marketed under different suggestive names, e.g., Spice, K2, Black Mamba, etc., for simplicity, we will refer to all products containing SCs as ‘Spice’ herein. Spice typically contains SCs that are sprayed onto an herbal substrate. Unlike delta-9-tetrahydrocannabinol (THC), the principal psychoactive constituent of herbal cannabis which is a weak partial agonist of brain cannabinoid receptors (CBRs), SCs are potent full CBR agonists (Weissman, Milne et al. 1982; Castaneto, Gorelick et al. 2014).

Spice products are marketed under the guise of potpourri, ...

Looks like you do not have access to this content.

Login

Don’t know how to login?

Click here for free trial login.

Back to Top

Copy and paste the following HTML into your website