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Glenn JH Dumont

In: The SAGE Handbook of Drug & Alcohol Studies Volume 2

Chapter 7: Cocaine: Pharmacokinetics, Pharmacodynamics and Addictive Potential

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Cocaine: Pharmacokinetics, Pharmacodynamics and Addictive Potential
Cocaine: pharmacokinetics, pharmacodynamics and addictive potential
Glenn JH Dumont
Introduction

Cocaine is a well-known recreational drug, used mainly for its stimulant properties. Cocaine is the product of the leaves of the coca plant (Erythroxylon coca). Cocaine has highly addictive properties, and although cocaine is an illegal substance, its use is relatively common. the number of cocaine users worldwide is in the range of 14 million to 21 million (0.3–0.5% of the population aged 15–64 years). Cocaine has been used at least once in their lifetime by 4.3% of the general population (EMCDDA, 2011). Cocaine is mostly used in developed countries; the largest markets are North America, Europe and South America (Pomara et al. 2012). Cocaine, usually a white powder, is typically ...

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