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Verena E. Metz & Sandra D. Comer

In: The SAGE Handbook of Drug & Alcohol Studies Volume 2

Chapter 6: Opioids: A Discussion of Pharmacokinetics and Pharmacodynamics in Those Who Misuse Drugs

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Opioids: A Discussion of Pharmacokinetics and Pharmacodynamics in Those Who Misuse Drugs
Opioids: A Discussion of Pharmacokinetics and Pharmacodynamics in Those Who Misuse Drugs
Verena E. MetzSandra D. Comer

Broadly speaking, people abuse opioid drugs for the pleasant effects they induce, such as euphoria, feelings of warmth and safety and pain relief. However, many variables contribute to the magnitude of the effects that are produced by each compound, including pharmacological characteristics of the drugs themselves, characteristics of the individuals using the drugs, and the external conditions under which the drugs are taken.

This chapter summarizes pharmacological and individual characteristics that may play an important role in the misuse/abuse of opioids in humans.

PHARMACOLOGICAL CHARACTERISTICS
Potency and efficacy

Two important concepts to consider when discussing the pharmacology of drugs are potency ...

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