• Summary
  • Contents
  • Subject index

With escalating healthcare costs, changes to the regulatory control on pharmaceutical industries and the inevitable adjustments made in policies and investment in healthcare there is enormous interest in the commercial as well as the scientific aspects of today's healthcare industry.

The SAGE Handbook of Healthcare provides an authoritative analysis of the current (and anticipated) developments in the global healthcare industries. Providing a unique perspective that interfaces between the science and business aspects, it combines information on the latest scientific developments with applied, commercial business data from the global marketplace.

The Handbook focuses on the aspects of paramount importance in the healthcare sector: Pharmacoeconomics; Pharmacogenomics; Therapeutics; Diagnostics

Areas covered include: The role of nanotechnology, genomics and cell therapy in medicine; Diagnostics; Biomarkers and technological advances; Case studies in oncology ...

Off-label Prescribing: Overcoming the Reimbursement Barrier
Off-label prescribing: Overcoming the reimbursement barrier
Overview

Off-label prescribing is the practice of using a medicine for a purpose other than that for which it has been officially approved. Off-label usage takes a variety of forms: departing from the dosing range or duration of therapy, using a medicine in an unapproved combination with another agent, prescribing a drug to patients who belong to populations for which the agent is not approved (notably children), and using the product for unlicensed indications.

A drug's initial label is often very narrow, and gaining approval for additional indications can take a long time. Manufacturers are understandably reluctant to conduct expensive clinical trials for new indications on drugs that have lost or will soon lose their patent ...

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