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By: Decision Resources Inc

In: The SAGE Handbook of Healthcare

Chapter 31: Prevention of Organ Transplant Rejection: Current Therapies and Novel Strategies

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Prevention of Organ Transplant Rejection: Current Therapies and Novel Strategies
Prevention of organ transplant rejection: Current therapies and novel strategies
The Need for New Antirejection Drugs

The practice of organ transplantation has expanded substantially since the first successful kidney transplant, more than 40 years ago. According to the Scientific Registry of Transplant Statistics (SRTR), about 25,000 transplants were performed in the United States in 2002, a 38% increase since 1993 (Organ Procurement and Transplant Network [OPTN]/SRTR 2004 Annual Report). Despite improvements in the rate of acute organ rejection following transplantation, organ loss remains a problem. Figure 31.1 shows graft survival rates for commonly transplanted organs over 10 years posttransplantation. Approximately 50% of the $5 billion spent annually in the United States on organ transplants is used for ...

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