- Subject index
With escalating healthcare costs, changes to the regulatory control on pharmaceutical industries and the inevitable adjustments made in policies and investment in healthcare there is enormous interest in the commercial as well as the scientific aspects of today's healthcare industry.
The SAGE Handbook of Healthcare provides an authoritative analysis of the current (and anticipated) developments in the global healthcare industries. Providing a unique perspective that interfaces between the science and business aspects, it combines information on the latest scientific developments with applied, commercial business data from the global marketplace.
The Handbook focuses on the aspects of paramount importance in the healthcare sector: Pharmacoeconomics; Pharmacogenomics; Therapeutics; Diagnostics
Areas covered include: The role of nanotechnology, genomics and cell therapy in medicine; Diagnostics; Biomarkers and technological advances; Case studies in oncology ...
Chapter 31: Prevention of Organ Transplant Rejection: Current Therapies and Novel Strategies
Prevention of Organ Transplant Rejection: Current Therapies and Novel Strategies
The Need for New Antirejection Drugs
The practice of organ transplantation has expanded substantially since the first successful kidney transplant, more than 40 years ago. According to the Scientific Registry of Transplant Statistics (SRTR), about 25,000 transplants were performed in the United States in 2002, a 38% increase since 1993 (Organ Procurement and Transplant Network [OPTN]/SRTR 2004 Annual Report). Despite improvements in the rate of acute organ rejection following transplantation, organ loss remains a problem. Figure 31.1 shows graft survival rates for commonly transplanted organs over 10 years posttransplantation. Approximately 50% of the $5 billion spent annually in the United States on organ transplants is used for ...